healing effect of Arnebia Euchroma in second degree burn wounds in rat as an animal model

Finding more efficient agents with fewer side effects for treatment of burns has always been a concern for researchers. Silver sulfadiazine [SSD], apparently due to its antimicrobial effect, is still one of the most common prescribed agents. Previous studies suggested that Arnebia euchroma [AE] has shown antimicrobial and anti-inflammatory activities. This study investigates the healing effect of AE extract in comparison with SSD in second degree burn wounds. Forty eight female Wistar rats [220 +/- 20 g] were divided into four groups. Standard second degree burn wounds were induced on the back of their necks. One group was treated with SSD; two groups were treated with AE cream at concentrations of 10% [AE10] and 20% [AE20] and the control group which received no treatment. The duration of treatment was 28 days. This study revealed that AE and SSD noticeably improved re-epithelization, fibroblasts proliferation, and collagen bundle synthesis and had a noticeable anti-inflammatory effect compared with the control group. Results of the present study revealed that Arnebia euchroma herbal extract was an effective treatment for second degree burn wounds when compared with SSD

[Determining the effect of zizphus jujba extract together with phototherapy in reducing bilirubin concentration in neonatal jaundice]

Neonatal jaundice is observed in the first week of birth among 60% of mature and 80% of immature neonates. This epidemic puts a lot of cost on the society. Today, phototherapy is used for the treatment of neonatal jaundice. Reducing the treatment period decreases the hospitalization costs. The Purpose of this study was to determine the effect of Zizphus Jujba extract and phototherapy on reducing both Bilirubin concentration and also the hospitalization period of neonatal jaundice patients. This was a clinical-trial study which was conducted at Imam Sajjad Hospital of Yasuj in 2009. 121 of the hospitalized neonates were chosen and divided into 2 groups: case group [63 neonates] and control group [58 neonates]. 1 cc of the Zizphus Jujba extract per each kilogram of body weight was orally given three times a day to the case group. Also phototherapy was used in the case group. Phototherapy was the only treatment used for the control group. The Bilirubin concentration of the hospitalized patients was measured two times a day in the hospitalization period. The collected data was analyzed by the SPSS software using t-test. The mean and standard deviation of the Bilirubin concentration in the control group before the intervention were 20.9 +/- 2.3 milligrams per 100 and after intervention was 12.27 +/- 1.23 milligrams per 100 while in the case group before intervention was 22.3 +/- 0.05 and after intervention was 12.27 +/- 1.01 milligrams per hundred. A significant difference was seen between the case and control group before and after intervention [p=0.001. Moreover, a meaningful reduction of the hospitalized days and a meaningful increase of excrement and urine in the case group were observed. This study revealed that administration of Zizphus Jujba extract with increasing amount of excrement and urine of the neonates can lead to Bilirubin discharge and can be effective on curing neonatal jaundice

Management of fractures in pyknodysostosis: a case report

Management of pathologic pycnodysostosis fracture of long bones with associated problems in a case of pycnodysostosis is reported. The clinical and pathologic findings are discussed