[Infections in inflammatory bowel disease]

Infections are frequent in inflammatory bowel disease and are associated with a high risk of mortality. To precise the risk factors of infections in patients with Crohn's disease and ulcerative colitis and to identify the prevention methods. Material and methods: Literature review. Some infections occur during the relapses of the disease and can explain the unfavourable outcome. It concern Clostridium difficile and Cytomegalovirus infections. Epstein-Barr virus infection is associated with an increased risk of lymphoma in patients on azathioprine. Opportunistic infections are relatively frequent in inflammatory bowel disease patients, especially in patients taking one or more immunosuppressors. Prevention of opportunistic infections is based on the pre-therapeutic screening before immunomodulatory agents and/or tumor necrosis factor antagonist initiation, vaccination in immune-compromised patients, and chemoprophylaxis in some conditions. Knowledge of infections in inflammatory bowel disease patients is important. Treatment of the infections could improve the response of the disease specific treatment and reduce the mortality related to opportunistic infections

[Inflammatory bowel disease and psoriasis about two cases]

Cutaneous manifestations of inflammatory bowel disease are relatively common. An association with psoriasis has been rarely observed. Case reports: We report the cases of two patients, 60 and 48 years old, suffering respectively from ulcerative colitis and Crohn's disease. The first patient had a 6 years history of plaque psoriasis. In the second case, skin lesions appeard simultaneously to the flare of inflammatory bowel disease. The association of inflammatory bowel disease and psoriasis may be explained by the similarity of genetic and immunological factors in both disorders