RESUMO
Nursing is a stressful job and nurses are confronted with so much stresses. Job stress currently has become a challenge for the nursing profession. Job stress can lead to a loss of creativity, job dissatisfaction, feeling of inadequacy, depression and reduced quality of nursing care. The present study was performed to investigate the relationship between personality characteristics and Job stress among medical staff in Saqqez Imam Khomeini's Hospital. In this correlation-descriptive study, 115 nurses from Saqqez Imam Khomeini's Hospital in 2013 were selected based on census sampling method. Data were collected by Expanded Nursing Stress Scale [ENSS] and NEO-Five Factor Inventory[NEO-FFI]. Data were analyzed by SPSS-18 software using descriptive statistics, independent t test, Pearson correlation and regression at the significant level of p