Evaluation of osteoporosis risk assessment instrument [ORAL] in Iranian postmenopausal women

Osteoporosis is a major health problem for postmenopatisal women and use of dual x-ray absorptiometry [DXA] is standard diagnostic method. But due to the cost, it is not economical to use for screening of all postmenopausal women, thus, the aim of this study was to evaluate performance of Osteoporosis Risk Assessment Instrument [ORAI] as a tool for screening of Osteoporosis among Iranian postmenopausal women. In this study data was collected from a bone densitometry centre. The Osteoporosis risk was evaluated for 341 postmenopausal women [age > 45 years] without consider secondary cause of Osteoporosis. The results were compared with their bone mineral density. From 341 postmenopausal women, 20.8% were showed osteoporotic and 39.6% had low bone mineral density in one or both studied area by DXA. To assess Osteoporosis of low bone mass, ORAI was shown a sensitivity of 70.9% and specificity of 66.9% respectively. The ORAI was adequate sensitivity to evaluate Iranian postmenopausal women. This test could be used as screen test to determinate low bone mineral density to referral of women

[Brown tumor of mandible in a patient with normocalcemic primary hyperparathyroidism]

Brown tumor or Osteitis Fibrosa Cystica [OFC] is a rare clinical entity complicating hyperparathyroidism. It may occur in the head and neck, with the mandible being the most frequent site. Primary hyperparathyroidism is usually associated with hypercalcemia. We report a 35 years old female with mandibular brown tumor secondary to primary hyperparathyroidism. In this case in spite of primary hyperparathyroidism and the bony lesion the serum calcium level was within normal limit. This case demonstrates that in osteolytic bony lesions a hyperparathyroidism complication can be expected even with normal serum calcium level. The presence of normocalcemia in hyperparathyroidism should prompt the physician to measurement of ionized calcium and look for vitamin D deficiency, magnesium deficiency, impaired renal function, use of interacting drugs and associated disorders. If there weren't these factors, normocalcemic primary hyperparathyroidism should be considered