Prevention of post operative nausea and vomiting PONV in day care surgery

Postoperative nausea and vomiting [PONV] is one of the unpleasant side effects in the postoperative period. The need for an effective antiemetic is increasing specially with the development of day care surgery. Many drugs were tried but heir clinical benefit and the most effective dose regimen were not established. In this study, 250 patients were operated upon on day care basis and were given either ondansetron, metoclopramide or placebo for prevention of PONV. It was found that the first drug had the highest success rate and the least incidence of side effects. Its use is recommended for day care surgical patients