RESUMO
The study was conducted on 150 normal healthy subjects of different age groups of both sexes (belonging to Jammu region only) to find out the pattern of physiological variations in the levels of the thyroid hormones viz. T3 (triiodothyronine), T4 (thyroxine) and TSH (thyroid stimulating hormone). The blood levels of T3, T4 and TSH of these subjects were found out by using radioimmunossay technique. The serum T3 and T4 levels decreased progressively with age with the highest levels being observed in children and lowest in the elderly. The serum T3 levels of males and females did not show any difference in any age group, whereas the mean serum T4 level in the adult females was more than that of adult male though the difference is statistically insignificant. There was, however, no difference between the serum T4 levels of males and females of children, adolescents and elderly groups. The mean serum TSH level was found to increase progressively with age and did not show any significant difference in males and females in any age group.
RESUMO
The study was undertaken on 24 human female postmenopausal subjects above the age of 50 years, to test the hypothesis that estrogen exerts regulatory influence on the autonomic nervous system in postmenopausal women. The parameters recorded and the test used were- pulse, blood pressure, orthostasis, cold pressor test, mental arithmetic and QTc interval for assessment of sympathetic activity and valsalva ratio, heart rate response, expiratory-inspiratory ratio (E.I. Ratio), standinglying ratio (S.L. Ratio) and 30:15 ratio for assessment of parasympathetic activity. Our findings show that the changes in sex hormone levels, after menopause may affect the autonomic system response, with increase in reactivity of both sympathetic and parasympathetic systems.
RESUMO
In fifty healthy adolescent girl volunteers serum calcium, magnesium and inorganic phosphorus were estimated serially during various menstrual phases. The result shows significant cyclic variations within physiological limits. Serum calcium was highest during ovulatory phase (p<O.OO I) and lowest during luteal phase (p<O.OO 1) as compared to other phases. The levels of serum magnesium were observed in opposite direction. It was highest during menstrual phase and lowest during ovulatory phase (p<O.OO 1). The highest levels of inorganic phosphrous were seen in menstrual phase as compared to other phases (p<O.OO I). The influence of cyclic variations of the ovarian hormones probably results in these changes.