Antibiotic susceptibility pattern of group b Streptococci isolated from pregnant women

Background: Antibiotic Resistance for Group B streptococci is a threat to health of newborn. Objective: To find out the antibiotic susceptibility pattern of the Group B Streptococci [GBS] isolated from pregnant women

Methodology: Fifty four isolates of Group B Streptococci were included in this study. All the strains were isolated from pregnant women who were observed to have colonized by Group B streptococci during the screening of a total 250 pregnant women. Antibiotic susceptibility testing was done using Kirby-bar disc diffusion test using five common antibiotics that are routinely used against gram positive cocci i.e. penicillin, tetracycline, vancomycin, erythromycin and clindamycin. Study was conducted from 1st January 31st to March 2014. SPSS version 16 was used for data analysis

Results: None of the fifty four isolates was found resistant to penicillin and vancomycin, while one isolate indicated resistance to erythromycin and three isolates were resistant to clindamycin

Conclusion: Consistent surveillance is required for antibiotics sensitivities of GBS and other bacteria implicated in newborn sepsis and maternal infections

Frequency of streptococcus agalactiae colonization in pregnant women in a tertiary care health center of Punjab

Background: Streptococcus agalactiae colonization in pregnant women may lead to transmission to newborn at delivery

Objective: To find out the frequency of Group B Streptococcus [GBS] colonization in the vagina and rectum of pregnant women

Methodology: Study Design: Across sectional study was carried out at Shaikh Zayed Hospital, Lahore. A total of 500 swabs [250 vaginal and 250 rectal] from 250 pregnant women of gestational age 35-37 completed weeks attending the gynaecology outdoor in Shaikh Zayed Hospital, Lahore were included in the study. Study Duration: Study was done from 1[st] June to 31[st] December 2012. The data analysis was done by using SPSS version 15

Results: A total of 250 pregnant women were enrolled in the study. GBS cultures were obtained from fifty four patients, corresponding to a colonization rate of 21.6%. Of the fifty four patients carrying GBS, the isolates recovered from vaginal swabs were nine cases [16.6%], and from rectal swabs were thirty seven cases [68.5%] while eight cases showed the recovery of GBS simultaneously from both vaginal and rectal swabs [14.8%]

Conclusion: GBS colonization in pregnant women is present in our population