RESUMO
In this study the demographic and clinical profile of 105 Yemeni children under 16 years old with sickle cell anemia [SCA] were studied. They were 53 males [50.4%] and 52 females [49.5%], aged between 0.5 and 15 years [mean 7.4ys]. The most serious crisis as vaso-oclusive, hemolytic, sequestration and aplastic crisis were seen in [83.8%], [52.3%], [6.6%] and [5.7%] respectively. The hand-foot syndrome was found in [21%] of all patients and in [51%] of children less than 3 years old. The most serious complication was the respiratory tract infections which was the most frequent in these patients, being encountered in [65.7%]. The rate of hospitalization was of [76%]. Our findings show that SCA has a severe clinical course in Yemenis, resembling that in black Africans and in black Americans
RESUMO
The present study aimed to examine whether maternal serum cytokines levels are useful for the diagnosis of preterm delivery with histologic chorioamnionitis. The blood samples of 16 women who delivered preterm, between 29 and 35 weeks of gestation, were collected at delivery and the placentae were histopathologically examined for chorioamnionitis. The mean value of interleukin-6 [IL-6] was significantly higher in six women with histologic chorioamnionitis than that in ten women without histologic chorioamnionitis [mean 234.4 pg/ml, range 100-312 pg/ml, mean 62.4 pg/ml, range 5-15 pg/ml, respectively]. The IL-6 level was statistically correlated with the level of C-reactive protein [CRP] in preterm women. The levels of interleukin-8 [IL-8] did not differ between the two groups. The results suggested that the level of maternal serum interleukin-6 is more useful than other markers including CRP for the identification of women at risk of impending preterm labor with histologic chorioamnionitis