RESUMO
Background: preterm labor is a major cause of perinatal morbidity and mortality and it might be predicted by assessing the cervical change
Objective: to assess the association between absences of cervical gland area [CGA] and spontaneous preterm labor [SPTL]
Materials and Methods: this prospective cohort study was performed on 200 singleton pregnant women with a history of SPTL, second-trimester abortion in the previous pregnancy or lower abdominal pain in current pregnancy. Each patient underwent one transvaginal ultrasound examination between 14-28 wk of gestation. Cervical length was measured and CGA was identified and their relationship with SPTL before 35 and 37 wk gestation was evaluated using STATA software version 10
Results: the mean of cervical length was 36.5 mm [SD=8.4], the shortest measurement was 9 mm, and the longest one was 61 mm. Short cervical length [=18mm] was significantly associated with SPTL before 35 and 37 wk gestation. Cervical gland area [the hypoechogenic or echogenic area around the cervical canal] was present in 189 [94.5%] patients. Absent of CGA had a significant relationship with SPTL before 35 and 37 wk gestation [p=0.01 and p<0.001, respectively]. Cervical length was shorter in women with absent CGA in comparison with subjects with present CGA: 37+/-10 mm in CGA present group and 23+/-9 mm in CGA absent group [p<0.001]
Conclusion: our study showed that cervical gland area might be an important predictor of SPTL which should be confirmed with further researches
RESUMO
Controversial findings exist regarding the association between neonate gender and umbilical cord blood lipid levels. This study aims to compare the levels of lipids and lipoprotein B-100 in the umbilical cord blood of male and female newborns and assess the impact of these factors on neonatal anthropometric measurements. This cross-sectional study was performed on 75 healthy, term [34 male and 41 female] newborns. A total of 5 ml of umbilical cord blood was obtained immediately after delivery and analyzed on the same day to estimate lipid concentrations and apolipoprotein B-100. Additionally, we measured and recorded neonatal anthropometric indicators. The independent sample t-test was used for comparison of mean values in the two groups. The relationship of cord blood lipid profile with anthropometric data was assessed by the Pearson correlation test and multiple linear regression. The cord blood from female newborns had higher levels of low density lipoprotein- cholesterol [LDL-C], high density lipoprotein-cholesterol [HDL-C] and total cholesterol [TC] compared to male newborns, whereas levels of lipoprotein B-100 and triglyceride [TG] were higher in males compared to female newborns. These differences were not statistically significant. In female newborns there was a significant inverse correlation between TG level and head circumference [P=0.038]. In males, there was no statistically significant association between lipid levels and anthropometric parameters. Gender did not impact lipid and apolipoprotein B-100 levels in newborns. This study showed a significant inverse correlation between TG level and head circumference in female newborns.