[Prospective epidemiologic study of group B streptococcus vaginal colonization in pregnant woman]

Group B streptococcus is known to be the principal medium responsible of maternal and severe neonatal infection. Assessing the prevalence of group B streptococcus [GBS] in our population, emphasize risk factors of GBS vaginal colonization and main characteristics of isolated strains. Prospective study of GBS vaginal colonization at admission for delivery upper to 34 amenorrhea weeks. Two hundred and seven vaginal swabs were carried out. Prevalence of GBS was 13%. Primigravida represents a risk factor of GBS vaginal colonization regarded to multigravida. False negative rate was 1,6%, All isolated strains were susceptible to penicillin C and to ampicilin, 44,4%were resistant to erythromycin. Systematic screening of GBS must be introduced in our population. Per partum antibioprophylaxis must consider susceptibility of isolated strains to antibiotics

Pseudomonas aeruginosa: etude multicentrique de la resistance aux antibiotiques [1999-2000]

A retrospective multicentric study was carried out over a period of 2 years [1999-2000]. 2659 strains of pseudomonas aeruginosa were collected from 4 university hospitals [charles Nicolle Hospital, pediatric Hospital and national center of Bone Marrow Transplantation in Tunis, Habib Bourguiba Hospital in Sfax]. Epidemiological profile and antibiotic susceptibility were analyesd. All bacteria were identified by conventional methods and antibiotic susceptibility tests were performed according to CA-SFM guidelines. The strains were recovered essrntially from surgical wards [33%] and intensive care units [22%]. Pseudomonas aeruginosa was isolated mainly from pus [36%] urine [32%]and respiratory samples [18%]. 25% of strains were resistant to ticarcilline, 18% to cefsulodine, 9% to ceftazidime, 14% to imipenem and amikacin and 25% to ciprofloxacin. Moreover, the resistance rates varied from hospital to hospital and from unit to another. The resistant strains were isolated particularly from urology and intensive care units: respectively 62% and 39% for ticarcilline; 26% and 13% for ceftazidime. The acquired resistance to b-lactams seems largely due to penicillinase production. The frequency of resistance to ceftazidime was the lowest and seem associated to chromosomal cephalosporinase over production

Evaluation of HPV oncogen risk in condyloma. A prospective study of 24 patients

Human papillomavirus [HPV] infection tend to be the most prevalent sexually transmitted disease [STD], and "high-risk" HPV types are correlated to intro-epithelial neoplasia, especially cervical cancer. - The aim of this study was to evaluate the frequency of "high-risk" HPV types in condylona. - Patients and methods: a non randomized prospective study was performed, including 24 patients with condyloma examined int the department of Dermatology of Charles Nicolle's hospital. Molecular hybridization method was realized for all patients to identify HPV type. - - Mean age of the 24 patients was 37.8 years. - Ratio [male/female]: 1.4 - In 21 patients HPV DNA was detected. - 2 women had "high risk" HPV type [9.5 percent]