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@#Objective To survey the value of risperidone in the treatment of depression without psychotic symptoms. Methods 205 depressive patients were randomly divided into 3 groups: risperidone group, fluoxetine group and combined group (risperidone+fluoxetine). They were assessed with Hamilton Depression Scale (HAMD), Treatment Emergent Symptom Scale (TESS) before treatment and in 2nd week, 4th week, 6th week and 8th week after treatment. Results The reduction rate of HAMD of combined group was the best among three groups(P<0.05), and that of fluoxetine group was better than that of risperidone(P<0.01). The significant difference in reduction rate of HAMD between combined group and other two groups was observed since 2nd week after treatment(P<0.05). No difference in scores of TESS has been observed in any time among three groups. Conclusion Risperidone can improve the efficacy of fluoxetine on depression without psychotic symptoms without increasing side effects, but itself is less effective than fluoxetine.
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Objective To study the effect of cognitive treatment on the compliance for medication and recrudescence of patients with schizophrenia.Method 106 schizophrenic patients were randomly allocated to the study and the control; both groups treated with antipsychotic medical treatment and health education, while the study group also accepted cognitive psychotherapy. Before treatment and at the ends of 0, 6, 12 months of treatment, the efficacy were investigated using the Brief Psychiatric Rating Scale (BPRS), Insight and Treatment Attitude Questionnaire (ITAQ) and Self-designed Compliance Survey in order to assess the compliance and the recrudescence. Results All the indexes after cognitive psychotherapy were significantly better than those before cognitive psychotherapy. Conclusion The cognitive psychotherapy can effectively reinforce the compliance of patients with schizophrenia, and then improve the quality of life for them.
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@#ObjectiveTo explore the cognitive psychological characteristics of the insomniac and the effect of cognitive therapy.Methods93 insomniac in-patients were divided randomly into the trial group (n=47) and control group (n=46). The trial group was treated by cognitive therapy plus medicine. The control group was only treated with medicines. The treatment lasted for 8 weeks. Before and after treatment, patients of all two groups were examined by Beliefs and Attitudes about Sleep Scale (DBAS). 45 healthy individuals were also examined at the same time. The therapeutic effect was evaluated with Pittsburgh Sleep Quality Index (PSQI).ResultsBefore treatment, DBAS scores of insomniacs were significantly different from the healthy (P<0.001). After treatment, scores of DBAS and PSQI of the trial group were significantly different from that of the control group ( P<0.001).ConclusionThe cognitive treatment can change erroneous cognitions related to sleeping in the insomniac and improve the therapeutic effect.
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Objective: To study alcohol related attention damage and factors having influence on it. Method: 39 inpatients with alcohol dependence were examined with Continuously Performance Test (CPT) before and after 6 weeks treatment. 45 normal staffs were collected as control. Results: The index of CPT in patient group at baseline was higher than that of normal control. After 6 weeks treatment, the above index declined but was still higher than control. The CPT results before treatment were related to plasma level of alcohol when admitted, age and history of alcohol use. Conclusion: Alcohol dose damage to the attention of patients in dependence.