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1.
Artigo | IMSEAR | ID: sea-212805

RESUMO

Background: Research of so many years from the procurable world data has shown that the reasons for most colorectal cancers occur due to change in life style the type of diet, smoking as well as the influence of the surrounding environment in which man lives and increasing age with only a minority of cases associated with genetic disorders. Colorectal cancer is the third most commonly diagnosed cancer. In the first half of the 20th century, mortality from colorectal surgery often exceeded 20%, mainly attributed to sepsis.Methods: The randomized prospective study was conducted on 202 colorectal cancer patients in the department of Colorectal division of General and Minimal Invasive surgery” Sher-i-Kashmir Institute of Medical Sciences, Srinagar.Results: Mean age of patients in Group 1 (with no mechanical bowel preparation (NMBP)) was 51±18.15 years while as same was 50±17.76 years for Group 2 (with mechanical bowel preparation (MBP)). Age range for Group 1 was 16-87 years and16-85 years for Group 2. Regarding outcomes, wound infections were 6.1% and 3.8% in Group 1 and Group 2 respectively. While disruption of anastomosis were 2.0% and 3.8% in group A and B respectively.Conclusions: Statistically no gross difference in terms of morbidity and mortality was found between the use of mechanical bowel preparation versus no use of mechanical bowel preparation in elective colorectal surgery. Elective Colorectal Surgery can safely be performed without enduring MBP in it as it does not possess any sorts of benefits.

2.
J. coloproctol. (Rio J., Impr.) ; 40(1): 43-49, Jan.-Mar. 2020. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1090842

RESUMO

Abstract Introduction The study is aimed to outline the vector of colorectal cancer incidence in the industrial Aktobe province of western Kazakhstan through the first decade of the screening implementation, 2009-2018. Methods Rough incidence rates and annual percent changes were estimated for each age group at diagnosis, ethnicities, gender, residences, the disease stages and anatomic subsites (total N 1128) via regression analysis. Results Within 2009-2018 colorectal cancer rates increased from 14.74 to 23.19, with annual percent changes of 4.69%. The most significant growth was traced in men compared to women, up to 28.39 by 2018, with annual percent changes 6.64% vs. 2.64% (p = 0.0009). Annual percent changes in Kazakhs reached 8.7%, whereas Slavic groups showed decline in the incidence, annual percent changes −4.3% (p = 0.002). Declining in rates was also observed in urban population compared to rural one, annual percent changes −3.3% vs. 17.6%, respectively. Patients aged 60-69 made 31% of all cases and showed the largest annual percent changes 9.37% (p = 0.002). Patients at Stage II made 61% of all observations, but general trend evidenced sharp growth in the group of Stage I (annual percent changes 28.91%, p < 0.0001). Conclusion Overall, during the last decade colorectal cancer incidence increased 1.5 fold with expected further rise. However, the increment of Stage I portion by 2018 vs. advanced stages at diagnosis and the trend to decrease in rates among urban population inspire a definite assurance in potential efficiency of the screening program in long run. The next researches on colorectal cancer should include scenarios to reveal the role of disadvantaged environment in the region and consuming unhealthy ultra-processed food.


Resumo Introdução O objetivo do estudo é delinear o vetor da incidência do câncer colorretal na província industrial de Aktobe, no oeste do Cazaquistão, durante a primeira década da implementação do rastreamento, 2009‒2018. Métodos Taxas de incidência brutas e alterações percentuais anuais foram estimadas para cada faixa etária ao diagnóstico, etnias, sexo, residências, estágios da doença e localizações anatômicas (N total de 1.128) através da análise de regressão. Resultados Entre 2009‒2018, as taxas de câncer colorretal aumentaram de 14,74 para 23,19, com alteração percentual anual de 4,69%. O crescimento mais significativo foi evidenciado em homens em comparação com as mulheres, até 28,39 em 2018, com alterações percentuais anuais de 6,64% contra 2,64% (p = 0,0009). Alterações percentuais anuais nos cazaques atingiu 8,7%, enquanto os grupos eslavos mostraram declínio na incidência, alterações percentuais anuais -4,3% (p = 0.002). O declínio nas taxas também foi observado na população urbana em comparação com a rural, alterações percentuais anuais -3,3% vs. 17,6%, respectivamente. Pacientes com idade entre 60‒69 anos eram 31% de todos os casos e apresentaram as maiores alterações percentuais anuais 9,37% (p = 0,002). Os pacientes no Estágio II eram 61% de todas as observações, mas a tendência geral evidenciou crescimento acentuado no grupo do Estágio I (alterações percentuais anuais 28.91%; p < 0,0001). Conclusão No geral, durante a última década, a incidência de câncer colorretal aumentou 1,5 vezes com expectativa de maior aumento. No entanto, o incremento da porção do Estágio I em 2018 em comparação com os estágios avançados no momento do diagnóstico e a tendência de diminuição nas taxas entre a população urbana inspira uma garantia definitiva de eficiência potencial do programa de rastreamento em longo prazo. As próximas pesquisas sobre o câncer colorretal devem incluir cenários para revelar o papel do ambiente desfavorecido na região e o consumo de alimentos ultraprocessados não saudáveis.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Adulto Jovem , Neoplasias Colorretais/patologia , Neoplasias Colorretais/epidemiologia , Incidência , Estudos Retrospectivos
3.
Artigo | IMSEAR | ID: sea-202842

RESUMO

Introduction: Extracorporeal shock-wave lithotripsy (ESWL)is an established non-invasive treatment modality for renaland ureteric stones. However, treatment outcome and efficacydepends on multiple factors like stone size, location and typeof machine used. We aimed to assess efficacy of ESWL asa primary treatment modality in renal and ureteric stones ina busy hospital setting having significant renal stone diseaseburden.Material and methods:1187 patients who underwent ESWLbetween January 2015 to December 2016 in our departmentwere included in the study. Patients with nephrolithiasis andureterolithiasis having functional kidney, without any absolutecontraindication to ESWL were included. Dornier Med TechCompact Delta 2 machines were used for all the patients.Stone localization was done using both fluoroscopic andultrasound- guided methods by same expert.Results: Out of 1187 patients,887 patients had solitary renalstones,170 had solitary ureteral calculus and 130 patients hadmultiple renal calculi. Stone size ranged from 8mm–20mm.Renal pelvic stones, upper calycial stones and proximalureteric stones had stone free rate of 84%,86% and 82.5%respectively. 89% and 84% of patients were stone free whensize of stone was between 8-12mm, it decreased to 77% and73% when size increased between 13-16mm for kidney andureteric stones respectively.Conclusions: ESWL is an effective primary treatmentmodality for appropriately selected patients with stone sizeless than 2 cm in favorable location with a normal functioningkidney. Use of both fluoroscopic and ultrasound imagingimproves localization of stones thus improving success. Itis an important modality in hands of urologist treating hugevolume of urolithiasis patients in busy hospitals with longwaiting list and with limited resources.

4.
Artigo | IMSEAR | ID: sea-212723

RESUMO

Background: Urological disorders like stone disease, pyonephrosis secondary to obstruction and trauma are common during pregnancy with global incidence of 1 in 250 to 1 in 3000. These diseases can complicate any pregnancy and timely diagnosis and management is of utmost importance for safety of the mother and fetus. Managing these cases entails morbidity and minimally invasive procedures avoiding anesthesia have definite advantage.Methods: It was an observational study. Pregnant patients with nephrolithiasis, pyonephrosis, complicated post-traumatic ureteropelvic junction (PUJ) obstruction (PUJO) and trauma were included in the study.Results: Out of total 84 cases, 45 required intervention. Percutaneous nephrostomy (PCN) for pyonephrosis secondary to PUJO and obstructed PUJ calculus was done in 11 and 14 cases respectively. Bilateral PCN for bilateral nephrolithiasis was done in 7 cases. Silicon double-J stenting for ureteric calculus was done in 13 cases. One case of spontaneous fornicial rupture of kidney without stone disease was managed conservatively as were 4 cases of trauma with concomitant renal injury, 18 cases of non-obstructive renal stones and 16 cases of pyelonephritis. Seven patients lost follow-up. One case each of pyonephrosis and polytrauma had fetal death at term unrelated to urological cause. In rest 75 patients, primary pathology was tackled after 6-8 weeks of delivery.Conclusions: Urological diseases during pregnancy are not an uncommon entity and can pose risk to both mother and fetus. With good clinical vigil, use of minimally invasive procedures, close monitoring and follow up, these patients can be safely managed without any adverse events to the fetus and mother.

5.
Arch. endocrinol. metab. (Online) ; 63(5): 495-500, Sept.-Oct. 2019. tab
Artigo em Inglês | LILACS | ID: biblio-1038504

RESUMO

ABSTRACT Objectives The differentiation between the various etiologies of thyrotoxicosis, including those with hyperthyroidism (especially Graves' disease [GD], the most common cause of hyperthyroidism) and without hyperthyroidism (like thyroiditis), is an important step in planning specific therapy. Technetium-99m (99mTc) pertechnetate thyroid scanning is the gold standard in differentiating GD from thyroiditis. However, this technique has limited availability, is contraindicated in pregnancy and lactation, and is not helpful in cases with history of recent exposure to excess iodine. The aim of this study was to identify the diagnostic value of the peak systolic velocity of the inferior thyroid artery (PSV-ITA) assessed by color-flow Doppler ultrasound (CFDU) and compare the sensitivity and specificity of this method versus 99mTc pertechnetate thyroid uptake. Subjects and methods We prospectively analyzed 65 patients (46 with GD and 19 with thyroiditis). All patients were evaluated with clinical history and physical examination and underwent 99mTc pertechnetate scanning and measurement of TRAb levels and PSV-ITA values by CFDU. The diagnosis was based on findings from signs and symptoms, physical examination, and 99mTc pertechnetate uptake. Results Patients with GD had significantly higher mean PSV-ITA values than those with thyroiditis. At a mean PSV-ITA cutoff value of 30 cm/sec, PSV-ITA discriminated GD from thyroiditis with a sensitivity of 91% and specificity of 89%. Conclusion Measurement of PSV-ITA by CFDU is a good diagnostic approach to discriminate between GD and thyroiditis, with sensitivity and specificity values comparable to those of 99mTc pertechnetate thyroid uptake.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Glândula Tireoide/diagnóstico por imagem , Tireoidite/diagnóstico por imagem , Doença de Graves/diagnóstico por imagem , Glândula Tireoide/irrigação sanguínea , Velocidade do Fluxo Sanguíneo , Sensibilidade e Especificidade , Pertecnetato Tc 99m de Sódio , Diagnóstico Diferencial
6.
Artigo | IMSEAR | ID: sea-209401

RESUMO

The aim of the present study is to investigate the rectal dose during three different radiotherapy techniques of dosimeter cervicalcancer. The study was carried out using a Anderson Rando female phantom. The thermoluminescent dosimetry (TLD) capsulesand detectors of rainbow dosimeter were employed for rectal and target volume dose determination. Several techniques ofexternal beam radiation therapy such as two field (AP-PA), three field, and four field with equal applied dose were planned.During application of different radiotherapy techniques, the maximum dose received by rectum is due to the two-field technique.The results of two dosimetry types were compared with each other. The mean and standard deviation values of two field, threefield, and four field for rectum are 1.97 ± 0.01, 1.68 ± 0.026, and 1.35 ± 0.05, respectively, whereas the mean and standarddeviation values of two field, three field, and four field for cervix are 2.03 ± 0.01, 1.98 ± 0.02 and 1.92 ± 0.01, respectively. Theresults were evaluated by the paired t-test. The P values calculated from data are as follows: Two field, cervix, P = 0.02; threefield, cervix, P = 0.0016; and four field, cervix, P = 0.0026, demonstrates that four field significantly reduces the rectum dose.This study showed that using TLD and rainbow dosimetry during radiotherapy could have a useful role as a predictor of choosingappropriate technique for preventing future rectal complications. Dose limitation to the rectum could possibly be achieved byusing three-field and four-field techniques with equal tumor dose while maintaining a high dose to the tumor.

7.
Artigo | IMSEAR | ID: sea-209264

RESUMO

Introduction: Worldwide, cervical cancer remains the most common gynecological cancer and the fourth most commonmalignancy in women, with over 526,000 women globally developing this tumor as reported in 2015 and 239,000 women dyingof the disease every year. To date, there are limited data of cervical cancer in Kashmir, India.Objectives: The aim of the present study was to analyze the demographic spectrum of cervical cancer in Kashmir.Materials and Methods: This was a retrospective study. All the patients who had histopathologically confirmed cervical cancer,registered at Regional Cancer Center of Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, were included, between2008 and 2015. All the patient characteristics including age, presentation, type of cancer, stage of cancer, parity, and treatmentreceived in each case were studied in detail.Results: The present study included 120 patients of cervical cancer. The median age of patients was 51 years. Majority of ourpatients were multiparous (88.3%) and from a rural background (74%). The most common presenting complaint was abnormal vaginalbleeding (70%) followed by abdominal pain (19%). Squamous cell carcinoma was the most common type of cervical carcinomaseen in 95% of patients followed by adenocarcinoma (5%). Most of the patients (66.67%) presented at late Stages (II, III, and IV).Conclusion: Early detection will reduce the number of deaths of cervical cancer patients. Asignificant number of cervical cancer patientsin Kashmir present with an advanced stage of disease. Cervical cancers are observed at a middle age group that is >40 years of age.People should be educated for an early consultation for symptoms, and high-risk individuals should be encouraged for screening. Thehealth programs about cervical cancer should be carried out in open places to give more information about cervical cancer to the public.

8.
Artigo | IMSEAR | ID: sea-202411

RESUMO

Introduction: Neglected cases of hemorrhoids presentingwith complications like strangulation are not uncommon,as observed in our tertiary care hospital. Under the abovebackground we conducted the present study to look into theprofile and management of the patients with complicated(especially strangulated) prolapsed hemorrhoids attending toour tertiary care hospital.Material and methods: This prospective hospital based studywas conducted in unit-II of department of general surgery inShri Maharaja Harisingh (SMHS) hospital Srinagar over aperiod of 5 years from January 2013 to December 2017. Allpatients with complicated prolapsed internal hemorrhoids(strangulation with infection, ulceration, gangrene, and/or necrosis) were enrolled in this study. Patients presentingwith features suggestive of complicated prolapsed internalhemorrhoids were subjected to clinical history, local inspectionand examination to confirm the diagnosis, and were managedappropriately.Results: During the study period of 5 years, 31 patients ofcomplicated (strangulated) prolapsed internal hemorrhoidswere enrolled. The age of our patients ranged from forty-fourto seventy-two years with mean age of 59.12±6.56 (SD=6.56)years. In our study 20 patients (64.5%) were from rural areaand 11 patients (35.5%) were from urban background. Mostcommon presentation in our study was strangulated prolapsedinternal hemorrhoid with pain, ulceration and infection.Conclusion: Patients with grade 3 and 4 internal hemorrhoids,patients having difficult access to health care facilities, andpatients having poor compliance to conservative treatment,should be offered surgical intervention at the earliest beforethe complications arise. Complicated prolapsed internalhemorrhoids can be managed initially conservatively (byprone position, bed rest, saline compresses, hot baths, icepacks, soothing topical applications, laxatives, antibiotics, sitzbath with antiseptic solutions)

9.
Artigo | IMSEAR | ID: sea-202213

RESUMO

Introduction: Management of infected wounds is notalways simple and easy. Vacuum-assisted closure (VAC) isa wound healing therapy that utilizes a dressing system thatcontinuously or intermittently applies a negative pressure tothe wound surface. Our aim was to assess the Feasibility andadvantages of simplified version of otherwise costly VAC, orsimple suction drainage in selected cases.Material and methods: This prospective study was conductedin the unit 2nd of department of surgery at SMHS hospital, anassociated hospital GMC Srinagar, over a period of 3 yearsfrom January 2014 to December 2016. During this period, 32patients were subjected to vacuum suction treatment and wereincluded in this study.Results: Wall suction (VAC) was used in 26 patients. MiniVac drain (USG guided) was used in 5 cases. In one patient ofscalp infection conventional large size suction drain was used.The time taken for the wounds to become healthy was 3 to7(average 3.5) days of VAC dressing or suction drainage. Noantibiotics were given during suction drainage in 21 patients.Need for grafting by split skin grafting method was felt in only2 patients. Mild discomfort (abnormal sensation) was reportedin 21 patients. Hospital stay for patients managed by suctiontherapy ranged from12 hours (breast abcess) to 16 days withan average of 7 days. The total cost incurred in the patientsundergoing VAC for a period of 15 days per patient was Rs.800 ($ 12).Conclusion: VAC seems to have revolutionary potential inthe management of the difficult to treat infected wounds asfar as its safety, speed and cost-effectiveness are considered.

10.
Artigo | IMSEAR | ID: sea-202159

RESUMO

Introduction: Neonatal hypernatremic dehydration is amedical emergency. Early diagnosis and appropriate treatmentis crucial for survival and better prognosis. However, diagnosisis often difficult due to apparent well being and dehydration isunderestimated. The aim of our study was to see the outcomeof neonates admitted with hypernatremic dehydration in ourhospitalMaterial and Methods: The study was conducted inneonatology of Postgraduate Department of Pediatrics, inGB Pant Hospital, an associated hospital of GovernmentMedical College Srinagar. It was a hospital based prospectiveobservational study conducted for 1 year, from March 2016to February 2017. A total of 67 neonates were enrolled in ourstudy.Results: The results showed mean age of presentation 18days, females were 37(55.5%), mean birth order was 1.6,44(65.7%) cases were from rural background,62 (92.5%) ofour cases were term babies, an average weight loss of 14.6%was found. There was a significant statistical relation in thepercentage of weight loss, incidence of shock, incidence ofAKI and sodium levels(p value<0.001).Conclusion: Women should be educated about theproper technique of breast feeding during prenatal visitsand after the delivery of the newborn. Mothers should beinformed about ‘ten steps of successful breast feeding’.All breast-fed infant should be weighed at least onceseveral days after discharge

11.
Artigo | IMSEAR | ID: sea-193948

RESUMO

Pheochromocytoma, a catecholamine secreting tumour, is rare and we are presenting such a case who presened with syncopal episodes due to arrhythmias associated with the tumour. The patient was managed with pharmacologic and surgical treatment.

12.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2018; 28 (11): 885-887
em Inglês | IMEMR | ID: emr-205221

RESUMO

Acute granulomatous interstitial nephritis [GIN] is a rare cause of acute kidney injury [AKI] but treatable. It is present in 0.5 to 0.9% of native renal biopsies. Treatment with moderate dosage of steroids is associated with good prognosis. We herein review a case of a 48-year lady having AKI following drug-induced damage [non-steroidal anti-inflammatory drugs [NSAIDs] and antibiotics]. Her renal functions did not improve after one month of drug withdrawal, so renal biopsy was done that showed acute GIN. She was treated with intravenous then oral steroids that completely resolved AKI

13.
Annals of Laboratory Medicine ; : 125-131, 2018.
Artigo em Inglês | WPRIM | ID: wpr-713435

RESUMO

BACKGROUND: Fungi, especially Aspergillus flavus, can cause chronic rhinosinusitis with nasal polyposis and modulate host innate immune components. The objective of this study was to examine the serum levels of T helper (Th) cell subset Th1, Th2, and Th17 cytokines and total IgE in patients having chronic rhinosinusitis with nasal polyposis and Aspergillus flavus infection. METHODS: A case-control study including 40 patients with chronic rhinosinusitis with nasal polyposis and 20 healthy controls was conducted. Aspergillus flavus infection was confirmed by standard potassium hydroxide (KOH) testing, culture, and PCR. Serum samples of all patients and controls were analyzed for various cytokines (interleukins [IL]-1β, IL-2, IL-4, IL-6, IL-17, IL-21, IL-27, TGF-β) and total IgE by ELISA. Data from patients with Aspergillus flavus infection and healthy volunteers were compared using the independent t-test and non-parametric Mann-Whitney U test. RESULTS: Aspergillus flavus infection was found in 31 (77.5%) patients with chronic rhinosinusitis with nasal polyposis. IL-1β, IL-17, IL-21, and TGF-β serum levels were significantly higher in these patients than in controls; however, IL-2, IL-4, IL-6, and IL-27 levels were lower. Compared with nine (22.5%) patients without Aspergillus flavus infection, IL-17 level was higher while IL-2 level was lower in patients with Aspergillus flavus infection. Total IgE was significantly higher in patients with Aspergillus flavus infection than in controls. CONCLUSIONS: High levels of IL-17 and its regulatory cytokines in patients with chronic rhinosinusitis with nasal polyposis infected by Aspergillus flavus raise a concern about effective disease management and therapeutic recovery. Surgical removal of the nasal polyp being the chief management option, the choice of post-operative drugs may differ in eosinophilic vs. non-eosinophilic nasal polyposis. The prognosis is likely poor, warranting extended care.


Assuntos
Humanos , Aspergillus flavus , Aspergillus , Estudos de Casos e Controles , Citocinas , Gerenciamento Clínico , Ensaio de Imunoadsorção Enzimática , Eosinófilos , Fungos , Voluntários Saudáveis , Imunoglobulina E , Interleucina-17 , Interleucina-2 , Interleucina-27 , Interleucina-4 , Interleucina-6 , Pólipos Nasais , Reação em Cadeia da Polimerase , Potássio , Prognóstico
14.
JPAD-Journal of Pakistan Association of Dermatologists. 2015; 25 (1): 44-51
em Inglês | IMEMR | ID: emr-171489

RESUMO

Fournier's gangrene is a serious condition with very high mortality. It is usually associated with various co-morbidities. Early diagnosis with multispecialty approach and aggressive management is the key to successful outcome. We successfully managed Fournier's gangrene in a 32-year-old diabetic male. This case is reported and the condition is reviewed in the light of recent literature


Assuntos
Adulto , Humanos , Masculino , Gangrena de Fournier/etiologia , Gangrena de Fournier/complicações , Diabetes Mellitus
15.
International Journal of Women's Health and Reproduction Sciences. 2014; 2 (2): 48-57
em Inglês | IMEMR | ID: emr-148604

RESUMO

To evaluate the female factors in infertility using laparoscopy in Kashmiri women. One hundred cases of infertility [primary and secondary] were included in this prospective study. Before the procedure, apart from complete history and detailed examination, baseline investigations [complete blood count, blood sugar, kidney and liver function tests, ECG, chest X-ray] were performed as per our institutional protocol for pre-anaesthesia check up. Laparoscopy was done in proliferative phase of menstrual cycle. To test the patency of tubes, chromotubation was done in all cases under laparoscopic vision by using 10-15 ml of autoclaved methylene blue dye. All the data was collected on pre-designed proforma and the results were tabulated and raw percentages calculated to describe the results. In primary infertility group [n=82], most common laparoscopic finding was tubal occlusion in 15 [18.3%], followed by endometriotic deposits in 14 [17.1%] patients. Other findings were polycystic ovaries in 10 patients [12.2%], peritubal and periovarian adhesions in 6 patients [7.3%], fibroids in 6 patients [7.3%], genital tract tuberculosis in 5 patients [6.1%], ovarian cysts in 4 patients [4.8%], hypoplastic uterus in 2 patients [2.4%] and pelvic inflammatory diseases in 2 patients [2.4%], in this group. The commonest finding by laparoscopy in patients with secondary infertility [n=18] was tubal occlusion in 5 [27.7%], followed by peritubal and periovarian adhesions in 4 [22.2%] patients. laparoscopy is very effective and cheap method in evaluating infertile women and should be considered earlier in infertility workup for effective and early treatment decisions


Assuntos
Humanos , Feminino , Laparoscopia , Infertilidade Feminina , Estudos Prospectivos
16.
JPAD-Journal of Pakistan Association of Dermatologists. 2013; 23 (3): 320-326
em Inglês | IMEMR | ID: emr-142945

RESUMO

Chondrodermatitis nodularis chronica helicis [CNCH] is a condition characterized by spontaneously evolving tender single or multiple nodules over the apex of helix or antihelix of the external ear. Various factors have been proposed to be the causative agents and different medical /surgical modalities of treatment have been devised. We review this disease in detail and present one such case which was managed on conservative lines.


Assuntos
Humanos , Masculino , Otopatias/diagnóstico , Otopatias/terapia , Doenças das Cartilagens/patologia
17.
JPAD-Journal of Pakistan Association of Dermatologists. 2013; 23 (2): 221-224
em Inglês | IMEMR | ID: emr-147409

RESUMO

Aplasia cutis is a disorder characterized by developmental absence of portion of skin. Scalp is the most commonly involved site. The etiopathogenesis of the disease is not fully understood and multiple theories have been proposed for explanation. The disorder occurs sporadically and cases with familial occurrence are very rarely mentioned in literature. One such case with familial aplasia cutis of scalp is reported in this article

18.
JPAD-Journal of Pakistan Association of Dermatologists. 2012; 22 (1): 12-18
em Inglês | IMEMR | ID: emr-128617

RESUMO

Dermal fillers have become exceedingly common globally in recent years for body rejuvenation, but with their widespread use and increasing profitability, cases of complications of dermal fillers are being widely reported. To document the complications related to dermal fillers as managed by the authors while working in different hospitals of Riyadh city. Demographic and clinical data of 47 cases, reporting with complications of dermal fillers over a period of two years from June 2009 to June 2011, were analysed. The complications were categorised by a self designed category system based on management and outcome. 44 females and 3 males, ranging in age from 23 years to 62 years were managed for complications of dermal fillers affecting face, hands, buttocks and external genitalia. 83% of cases had moderate to severe complications, and 51% were unaware of the nature of dermal filler received by them. 20 cases [42.5%] required surgical treatment and interventions under anesthesia. With increased use of dermal fillers, the complications are also being frequently encountered. Dermatologists should be wary of these avoidable untoward effects and their proper management


Assuntos
Humanos , Masculino , Feminino , Rejuvenescimento , Face , Mãos , Nádegas , Genitália , Ácido Hialurônico/efeitos adversos , Colágeno/efeitos adversos
19.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2011; 21 (2): 109-110
em Inglês | IMEMR | ID: emr-103674

RESUMO

Mucormycosis is a fulminant and uncommon fungal infection of skin which mostly occurs in immunocompromised patients. Early diagnosis followed by aggressive debridement and administration of antifungal agents is the key to management. We report primary cutaneous mucormycosis in a 23 years old patient of acute leucocytic leukemia who developed this lesion over volar surface of right forearm at the site of intravenous cannulation during induction phase of chemotherapy. The condition was treated successfully by wide surgical debridement, amphotericin-B, wound care and definitive reconstruction with skin graft


Assuntos
Humanos , Masculino , Leucemia , Mucormicose/terapia , Antebraço , Desbridamento , Anfotericina B , Transplante de Pele , Hospedeiro Imunocomprometido
20.
Pakistan Oral and Dental Journal. 2011; 30 (2): 273-276
em Inglês | IMEMR | ID: emr-109882

RESUMO

The authors present a review of 86 patients with bony ankylosis of Temporomandibular joint treated between Jan 1990 and Dec 2005 at a tertiary care referral hospital in Srinagar. Childhood trauma was the leading cause of ankylosis. For initial 50 patients of the series, acrylic spacer was used as interpositional material, and for the rest of patients, silicone block was used. Follow-up evaluation ranged from 14 months to five years [average 31 months]. Recurrence was observed in 5 patients [all in acrylic group]. There was statistically no significant difference in post operative mouth opening and other complications between the two groups. The aim of the study was to analyze the treatment outcome of the patients with TMJ ankylosis


Assuntos
Humanos , Pré-Escolar , Criança , Adolescente , Adulto , Masculino , Feminino , Anquilose/cirurgia , Transtornos da Articulação Temporomandibular/cirurgia , Resultado do Tratamento
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