RESUMO
We report the case of a 58-year old patient, showing a solid image in the right kidney, who underwent radical nephrectomy that revealed neoplasia, whose pathological study led to the diagnosis of kidney carcinoma associated with Xp11.2 translocation / TFE3 (ASPL-TFE3) gene fusion. The authors discuss aspects related to this lesion, such as frequency, pathogenesis, clinical presentation, histopathology and outcome, as observed in the literature.
Assuntos
Feminino , Humanos , Pessoa de Meia-Idade , Carcinoma de Células Renais/genética , Cromossomos Humanos X/genética , Proteínas de Ligação a DNA/genética , Neoplasias Renais/genética , Fatores de Transcrição/genética , Translocação Genética/genética , Fatores de Transcrição de Zíper de Leucina e Hélice-Alça-Hélix Básicos , Carcinoma de Células Renais/patologia , Neoplasias Renais/patologiaRESUMO
We report the case of a 57-year old patient with complex cystic image in right kidney. Following radical nephrectomy, the pathological study established the diagnosis of renal cholesteatoma. We discuss the frequency, pathogenesis, clinical presentation, propedeutics, histological findings and proposes for intervention observed in the literature.