RESUMO
We report the success of oral cyclosporine therapy in a patient with severe vision-threatening vernal keratoconjunctivitis. A child presented with severe allergy which was not controlled with topical steroids, cyclosporine and mast cell stabilizers. Oral steroids were required repeatedly to suppress inflammation. Child showed a dramatic improvement and stabilization with oral cyclosporine therapy. Oral cyclosporine therapy can be tried in severe vision-threatening allergy refractory to conventional therapy.
Assuntos
Administração Oral , Criança , Túnica Conjuntiva/patologia , Conjuntivite Alérgica/diagnóstico , Conjuntivite Alérgica/tratamento farmacológico , Córnea/patologia , Ciclosporina/administração & dosagem , Relação Dose-Resposta a Droga , Resistência a Medicamentos/efeitos dos fármacos , Seguimentos , Glucocorticoides/uso terapêutico , Humanos , Imunossupressores/administração & dosagem , Masculino , Estudos Retrospectivos , Índice de Gravidade de DoençaRESUMO
We report a case of surgically induced necrotizing scleritis following pterygium surgery with the bare sclera technique, without the use of adjunctive irradiation or mitomycin C. The patient was successfully treated with systemic immunosuppression.
Assuntos
Feminino , Seguimentos , Humanos , Imunossupressores/uso terapêutico , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Oftalmológicos/efeitos adversos , Complicações Pós-Operatórias , Pterígio/cirurgia , Esclerite/tratamento farmacológicoRESUMO
We report a case of nocardiosis in a 42, years male with common variable immunodeficiency syndrome (CVID). He presented with arthritis, subcutaneous abscess and pleural effusion. Diagnosis of CVID was made during this presentation. Serum IgG, IgA and IgM levels were markedly decreased. Nocardia asteroides was cultured from pleural fluid. He was successfully treated with intravenous immunoglobulin and cotrimoxazole.