Joint restriction in adult non-insulin-dependent diabetes mellitus

100 patients suffering from adult non insulin dependent diabetes mellitus for a duration varying between one year and 15 years were included study. 35 age and sex matched controls not suffering from diabetes were also included in the study. The mobility score recommended by Campbell et al. [1985] was used to assess joint restriction in both groups. The diabetics were divided into 2 groups; group A [patients with joint restriction] and group B [patients without joint restriction]. 48% [48/109] of the diabetics had joint restriction while 8.57% [3/35] of the control group had joint restriction. The mobility score was significantly poorer in the diabetics than in patients of control group [P < 0.05]. The mobility score was poorer in patients who had diabetes for more than 10 years [P < 0.0001], 25% [12/48] of diabetics with joint restriction and all of them had diabetes for more than 10 years. The incidence of intake of insulin in group A patients [diabetics with joint restriction] was 87, 80% while its incidence in group B patients [diabetics without joint restriction] was 61.5% while is statistically significant [P < 0.001]. The incidence of micro-vascular disease of eyes and kidneys in group A was 43.75% while its incidence in group B was 22% which is statistically significant [P < 0.02]. The incidence of neuropathy in group A was 33.33% while its incidence in group B was 11.53% which is statistically significant [P < 0.001]. The incidence of tight waxy skin over proximal phalanges was 60.4% in group A while its incidence in group B was 1r90.2% which is statistically significant [P < 0.0001]

study for the role of histamine-H2-antagonist in the healing of non steroidal anti-inflammatory induced peptic ulcer in rheumatoid arthritis patients

22 patients suffering from rheumatoid arthritis with sustained indomethacin induced peptic ulceration were included in the study, they were 17 females and 5 males with their ages varying between 35 and 65 years. Their initial endoscopic finding was recorded and they were then randomly allocated into 2 groups. Group 1: consisted of 11 patients who were put on Ranitidine 150mg twice daily and alluminium hydroxide 20ml. 4 hourly in addition to the dose of indomethacin which induced peptic ulceration. Group 2: consisted of 11 patients who received placebo twice daily and aluminium hydroxide 20ml, 4 hourly in addition to the dose of indomethacin which induced peptic ulceration. After 8 weeks endoscopy was repeated, the incidence of healing in group 1 was 90,9% [10/11] in comparison to 45,45% [5/11] in group 2, which was statistically significant [P <0, 01]

Salmonellae as a bacterial cause of diarrhea in newborn calves

Fecal swabs collected from 719 newborn diarrheic calves belonging to the Dairy Project in Libya were examined bacteriologically for the isolation and identification of Salmonella microorganisms. Out of these, 249 animals proved to harbor salmonellae [34.63%]. S. newport was the most prevalent serotype isolated [59.44%]. On the other h and, S. typhimurium, S. muenchen and S. enteritidis could be detected in an incidence of 23.69%, 9.24% and 7.63%, respectively. Most of the isolated strains were tested to nine antibiotics in vitro by using the filter paper disc method