1.
Egyptian Journal of Psychiatry [The]. 1992; 15 (1): 53-65
em Inglês
| IMEMR
| ID: emr-23559
RESUMO
This study evaluates the potential antidote action of naloxone on experimentally induced diazepam and flunitrazepam [benzodiazepines] intoxication in dogs. Its antidote effects is also evaluated in a clinical sample of 8 patients suffering from flunitrazepam intoxication. The clinical findings were suggestive of an antagonistic action of naloxone in flunitrazepam intoxication. It was also found that flunitrazepam exhibits a different pharmacological profile from other members of the benzodiazepine group. Our findings of a selective naloxane-flunitrazepam reversal need to be explained in relation to the mechanism of action of this benzodiazepine, as well as to the equated naloxane-opiates reversal
Assuntos
Diazepam/efeitos adversos , Transtornos Relacionados ao Uso de Substâncias , Suicídio , Ansiolíticos , Flunitrazepam , Benzodiazepinas/antagonistas & inibidores
2.
Egyptian Journal of Psychiatry [The]. 1992; 15 (1): 81-88
em Inglês
| IMEMR
| ID: emr-23562