A Case of the Oculopharyngeal Muscular Dystrophy

The oculopharyngeal muscular dystrophy is a distinct, clinically well-defined myopathy of later life inherited in an autosomal dominant fashion with complete penetrance. Blepharoptosis, dysphagia, lower leg weakness are the most prominent findings. It is a systemic myopathy which affects all voluntary muscles and appears to spare smooth and cardiac muscle. The authors experienced a case of the oculopharyngeal muscular dystrophy which showed characteristic signs and symptoms such as symmetric ptosis, dysphagia, and progressive external ophthalmoplegia, and the literature were reviewed.

AC/A Ratio Measured by Modified Gradient Method

A clinical study on the AC/A ratio with 125 normal persons was performed by modified gradient method. AC/A ratio is a convergence response of an individual to a unit stimulus of accommodation. Through many studies on the AC/A ratio, the normal range of the AC/A ratio was 3 delta/D ~ 5 delta/D. The AC/A ratio can be changed by some drugs. The AC/A ratio is high in divergence excessive exotropia, pseudodivergence exotropia and non-refractive accommodative esotropia; on the other hand, the AC/A ratio is low in convergence insufficiency exotropia. Methods for the determination of the AC/A ratio are heterophoria method, gradient method, fixation disparity method. This study was performed by modified gradient method due to easy application. The mean of the AC/A ratios in this study was 4.55 delta/D, and the AC/A ratios ranged from 0.5 delta/D to 9.6 delta/D. 95 percentile ranged from 3.01 delta/D to 6.09 delta/D. The AC/A ratio in this study seems not to be correlated with age, sex and interpupillary distance.

AC/A Ratio Measured by Modified Gradient Method

A clinical study on the AC/A ratio with 125 normal persons was performed by modified gradient method. AC/A ratio is a convergence response of an individual to a unit stimulus of accommodation. Through many studies on the AC/A ratio, the normal range of the AC/A ratio was 3 delta/D ~ 5 delta/D. The AC/A ratio can be changed by some drugs. The AC/A ratio is high in divergence excessive exotropia, pseudodivergence exotropia and non-refractive accommodative esotropia; on the other hand, the AC/A ratio is low in convergence insufficiency exotropia. Methods for the determination of the AC/A ratio are heterophoria method, gradient method, fixation disparity method. This study was performed by modified gradient method due to easy application. The mean of the AC/A ratios in this study was 4.55 delta/D, and the AC/A ratios ranged from 0.5 delta/D to 9.6 delta/D. 95 percentile ranged from 3.01 delta/D to 6.09 delta/D. The AC/A ratio in this study seems not to be correlated with age, sex and interpupillary distance.

Immunohistochemical Test of Pseudolymphoma

Pseudolymphoma, the term clinically synonymous with pseudotumor, is one of the lymphoproliferative disease which frequently causes unilateral proptosis in adults. The clinical manifestations and the pathologic pictures may resemble that of a true neoplasm. Recently, immunologic methods such as immunofluorescent and immunohistochemical study were popularly used in the diagnosis and study of lymphoproliferative diseases. We have experienced three cases of pseudolymphoma of the orbit which were diagnosed with PAP(proxidase-antiperoxidase) stain of the immunohistochemical method.