4 Cases of Duchenne type of Progressive Muscular Dystrophy

4 cases of Duchenne type of Muscular Dystrophy have been experienced in brothers of 6 years old boy, 8 years old boy whose limb girdle was involved, brothers of 9 years old boy and other brothers of 9 years old boy. Ina all cases, serum CPK levels were significantly increased and typical waddling gait and Gower's sigh were noticed. The muscle biopsy findings and electromygraphic findings were also compatible with progressive muscular dystrophy.We report with brief review of literatures.

Four Cases of Anencephaly with Multiple Anomalies

The incidence of anencephaly ranges from 0.1 to 6.7 per 1,000 births. Female fetuses predominated, especially among prematures, with a ratio of between 3 and 7 to 1. The infants are either stillborn or die within a few days of birth. By about 23 days?gestational age the neural tube is complete, except for an opening at each end, the anterior and posterior neuropores. Failure of closure of the anterior neuropore causes anencephaly. Ultrasound scanning of the skull in the anencephalic fetus, measurement of alpha-fetoprtein countent in amniotic fluid may also ve of help in rntrauterine diagnosis. Four cases of anencephaly with mutiple anomalies experienced at nursery of Kyung Hee University Hospital were reported with brief review of related literaures.