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1.
Korean Journal of Pediatric Hematology-Oncology ; : 376-382, 1997.
Artigo em Coreano | WPRIM | ID: wpr-74306

RESUMO

OBJECT: Pre-ALL is a very rare preteukemic state, which percedes acute lymphocytic leukemia, while MDS(pre-ANLL), usually the well-known type of preleukemic state, precedes acute non-lymphocytic leukemia. Initially it shows transient pancytopenia without any evidence of leukemia in bone marrow findings, followed by acute lymphocytic leukemia after recovery from pancytopenia of a short period within weeks or months. We report a case with pre-ALL in childhood. CASE: A 15-month-old male baby was admitted with the complaints of fever and cough for 5 days and pallor for 2 weeks prior to admission. On admission, CBC showed pancytopenia without any evidence of leukemia, which was recovered spontaneously in a short period, and then was followed by acute lymphocytic leukemia of CALLA negative, early pre-B cell type. During antileukemic chemotherapy, he had suffered from severe bacterial infections and was finally died of sepsis 8 months after first admission. CONCLUSION: We report a case of pre-ALL in childhood, which was preceded by CALLA negative, early pre-B cell ALL, with a review of the literatures, briefly.


Assuntos
Humanos , Lactente , Masculino , Infecções Bacterianas , Medula Óssea , Tosse , Tratamento Farmacológico , Febre , Leucemia , Palidez , Pancitopenia , Leucemia-Linfoma Linfoblástico de Células Precursoras , Células Precursoras de Linfócitos B , Sepse
2.
Journal of the Korean Pediatric Society ; : 131-135, 1996.
Artigo em Coreano | WPRIM | ID: wpr-65705

RESUMO

We experienced a case of idiopathic crescentic glomerulonephritis in a 10-year-old girl who was admitted to our hospital due to gross hematuria and oliguria for 2 months. The diagnosis was based on the rapidly progressive clinical course to chronic renal failure, positive p-ANCA test and light microscopic findings of diffuse crescents formation in about 80% glomeruli of renal tissue obtained by percutaneous renal biopsy. Our case was treated with high dose methylprednisolone ( 30mg/Kg) pulse therapy whenever its clinical course was aggravated for several times. After 2 years 6months later, she has been treated on peritoneal dialysis. A review of literatures was also presented briefly.


Assuntos
Criança , Feminino , Humanos , Anticorpos Anticitoplasma de Neutrófilos , Biópsia , Diagnóstico , Glomerulonefrite , Hematúria , Falência Renal Crônica , Metilprednisolona , Oligúria , Diálise Peritoneal
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