A Case of Pancreatitis associated with Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE), an autoimmune disease with multisystemic involvement, has been reported to be associated with a number of gastrointestinal complications. But pancreatitis is an unusual complication of SLE, occuring in only 3-4% of lupus cohort. Multiple mechanisms contributing to pancreatitis associated with SLE have been demonstrated which include vasculitis, necrotizing pancreatitis, corticosteroid administration, and vascular thrombosis. We experienced a case of pancreatitis associated with SLE in a 14-year-old girl. The cause of pancreatitis may be related secondarily to vascular thrombosis, since there were several clinical and laboratory findings suggesting thromboembolic phenomena, including false-positive test for syphilis, prologation of PT/aPTT, and pulmonary embolism.

A Case of Pancreatitis associated with Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE), an autoimmune disease with multisystemic involvement, has been reported to be associated with a number of gastrointestinal complications. But pancreatitis is an unusual complication of SLE, occuring in only 3-4% of lupus cohort. Multiple mechanisms contributing to pancreatitis associated with SLE have been demonstrated which include vasculitis, necrotizing pancreatitis, corticosteroid administration, and vascular thrombosis. We experienced a case of pancreatitis associated with SLE in a 14-year-old girl. The cause of pancreatitis may be related secondarily to vascular thrombosis, since there were several clinical and laboratory findings suggesting thromboembolic phenomena, including false-positive test for syphilis, prologation of PT/aPTT, and pulmonary embolism.

A Case of Spondyloepiphyseal Dysplasia Congenita

Spondyloepiphyseal dysplasia congenita is one of the osteochondrodysplasia, used to be diagnosed by clinical symptoms and radiologic findings. Clinical findings are short-trunk dwarfism, oval face, hypertelorism, short neck, kyphosis, lordosis, joint instability, coxa vara, pectus excuvatum, cleft palate, severe myopia, retinal detachment, deafness, and radiologic findings are thoracic kyphosis, lumbar lordosis, platyspondyly, anterior flaring of ribs, delayed ossification of head of humerus and femur, delayed ossification of pubic bone, short femoral neck, often metaphyseal irregularity. The etiology was known as only family disorder, at now a gene mutation of COL2A1 at chromosome 12. So it is classified as the type II collagenopathy. Authors had experienced a case of spondyloepiphyseal dysplasia congenita with clinical and radiologic findings.

A Case of Ischemic Colitis in Childhood

Ischemic colitis is a common gastrointestinal disease not in childhood but in sixties decade. It's developed due to ischemic injury of colon and classified to transient reversible form, chronic form and acute fulminant form. Uniquely Authors had experienced a case of ischemic colitis diagnosed as barium enema in childhood. This patient was brought to our hospital due to abdominal pain, abdominal distension and bloody diarrhea. He was received barium enema study which showed stricture of splenic flexure of descending colon. He had severe clinical course of ischemic colitis, resulting in sepsis and acute renal failure. He was recovered from previous symptom after hemodialysis, antibiotic medication and supportive care. We saw recovery of stricture of splenic flexure by barium enema study.

Correlation between Plasma Endothelin-1 Concentrations and Pulmonary Hypertension Associated with Congenital Heart Defects

PURPOSE: Endothelin-1 is the most potent vasoconstrictor. This study was investigated the correlation of plasma endothelin-1 and pulmonary hypertension associated with congenital heart defect. METHODS: We evaluated the concentration of ET-1 in 24 cases of congenital heart disease diagnosed at the Department of Pediatrics, Pusan National University, from December 1993 to September 1994. The patients were divided into 2 groups according to mean pulmonary arterial pressure: Pulmonary artery hypertension group(Group I) and normal pulmonary artery pressure group(Group II). Between 2 groups, there was no statistical significance in mean age, sex and oxygen saturation. GroupI included 9 patients of VSD and 1 patient of COA. Group II included 9 patients of VSD, 3 patients of TOF and 1 patient of PS, 1 patient of PS with DORV. RESULTS: The results were summarized as follows; 1) The mean pulmonary arterial pressure and pulmonary-to-systemic flow ratio (Qp/Qs), pulmonary vascular resistance in GroupIwere significantly higher than those in Group II. 2) The plasma concentrations of ET-1 in GroupI was significantly higher than those in Group II. 3) But there were no statistical significance between the concentrations of ET-1 and the mean pulmonary artery pressure, Qp/QS, pulmonary vascular resistnace. CONCLUSIONS: Based on these results, plasma ET-1 concentraions were elevated in patients with pulmonary hypertension associated with congenital heart defects.

A Case of Hyperthyroidism Following Primary Hypotyroidism

No abstract available.

Primary Hyperparathyroidism in Children / 대한내분비학회지

Primary hyperparathyroidism is a rare endocrine disease in children. It involves bone and joint, urinary tract, gastrointestinal tract and cardiovascular system. The main cause of these involvement is high level of PTH in serum, resulting in hypercalcemia.An 11 years old male patient who had complained of limping gait since last 18 months, showed typical laboratory and radiological findings of primary hyperparathyroidism. At the ultrasonography, computed tomography and radionuclide scanning, a well defined mass(10 X 15mm) was found on the posterior aspect of the right thyroid lobe. The mass was confirmed histologically as adenoma of parathyroid gland. The patient was successfully treated with subtotal parathyroidectomy and temporal administration of calcium and vitamin D.We report this case of primary hyperparathyroidism with brief review of the literatures.