Clinical Effect of Ureaplasma Urealyticum Colonization of Maternal Low Genital Tract and Premature Respiratory Tract on Neonatal Adverse Outcome

PURPOSE: Ureaplasma urealyticum (UU) colonization in maternal low genitourinary tract can cause preterm labor, spontaneous abortion, and chorioamnionitis. Also preterm babies suffer from perinatal mortality and morbidity. The purpose of this study was to determine the clinical effect of UU colonization in maternal vaginal fluids and premature respiratory secretions on neonatal adverse outcomes. METHODS: Retrospective review were performed on preterm baby less than 35 weeks and their mother who were admitted at Kangnam Sacred Heart Hospital, Hallym University from October, 2010 to June, 2012. Maternal vaginal specimen, preterm baby's tracheal fluid and nasopharynx secretion were collected and PCR and/or culture tests were done. The subjects were divided into 4 groups; both maternal and preterm colonization positive were 'UUA' group, only maternal colonization positive as 'UUB', only preterm colonization positive as 'UUC', and both maternal and preterm colonization negative as 'UUD'. Variable clinical outcome were investigated. RESULTS: A total of 170 data were collected from the preterm delivery mother and their babies. The overall prevalence of maternal UU was 51% (86/170) and the prevalence of neonatal colonization was 39% (66/170). Of those 4 groups, gestational age (28.5+/-3.0 week, P=0.000) and birth weight (1,208.8+/-451 g, P=0.000)were the smallest in UUA. Also, prevalence of histological chorioamnionitis (P=0.040) and bronchopulmonary dysplasia (P=0.000) were statistical higher in UUA. CONCLUSION: Maternal colonization of UU was associated with histological chorioamnionitis. Maternal UU colonization and preterm respiratory secretion was associated with bronchopulmonary dysplasia.

Psychologic Characteristics in Caregivers of Children with Attention Deficit Hyperactivity Disorder / 대한소아신경학회지

PURPOSE: ADHD (Attention Deficit Hyperactivity Disorder) is a neurodevelopmental disorder with three characteristics, such as impulsivity, inattention, and hyperactivity symptoms. This is a common disease that the prevalence reaches 4-7% of all children. There are a variety of hypothesis in the pathogenic mechanisms and etiology. Parental psychopathology influences directly and indirectly on the occurrence of ADHD in children. The aim of this study was to evaluate the clinical and psychological characteristics of caregiver of child with ADHD using the MMPI (Minnesota Multiphasic Personality Inventory)-2. METHODS: The subjects consisted of 35 caregivers of patients with ADHD and 34 caregivers of children without neuropsychiatric disorders who visited to the pediatric neurology clinic of Kangnam sacred heart hospital from January 2009 to June 2011. We diagnosed ADHD according to DSM(Diagnostic and Statistical Manual of Mental Disorder)-IV criteria. We compared the psychologic characteristics between ADHD group and control group using T score of MMPI-2. RESULTS: MMPI T scores of caregivers of children with ADHD were significantly higher on the depression(D), psychasthenia(Pt), schizophrenia(Sc), social introversion (Si) scales than control group and most of scales were significantly higher in restructured clinical (RC) scale and personality psychopathology five (PSY-5) scales. CONCLUSION: The results suggested that psychopathology of caregivers might induce ADHD in the children. On the contrary, ADHD symptom of children might be associated with occurrence of psychopathology in the cargiver. In order to proper treatment of ADHD patient, we need to psychologic evaluation in the caregivers of patients with ADHD.