RESUMO
ABSTRACT Sporotrichosis is a neglected mycosis that affects human and animal hosts, including domestic cats. In Brazil, its most frequently diagnosed etiological agent is Sporothrix brasiliensis. Zoonotic transmission of S. brasiliensis occurs via direct contact between an infected cat and a susceptible human host. Notification of confirmed cases of feline sporotrichosis is not mandatory in Brazil. The metropolitan area of Goiania city can be considered a silent area for the occurrence of feline sporotrichosis. In this context, voluntary reporting of feline sporotrichosis cases is recommended for all healthcare professionals. This study aimed to report the first occurrence of S. brasiliensis in a cat from the metropolitan area of Goiania city. Cytopathology, mycology, thermal dimorphism and calmodulin gene amplification tests were performed. The mycological and molecular biological diagnoses corresponded to S. brasiliensis. The etiological agent of zoonotic sporotrichosis was detected in the metropolitan area of Goiania city, and therefore there is a risk of the emergence of new cases of cats infected with S. brasiliensis and the occurrence of zoonotic transmission of this fungus.
RESUMO
ABSTRACT: Gallus gallus domesticus' immune system is a promising tool for generation of antibody-based immunobiologics. Immunoglobulin y (IgY) is extracted from egg yolk and has equivalent functions to mammal's igg antibody. Avian immune system can be stimulated to produce a high-quality antibody repertoire. In this review, we present an overview of avian immune system emphasizing igy and its applications as an immunobiologic.
RESUMO: O sistema imunológico deGallus gallus domesticus é uma ferramenta promissora para a geração de imunobiológico a partir de anticorpos. A imunoglobulina Y (IgY) é extraída da gema do ovo e apresenta funções equivalentes ao anticorpo IgG dos mamíferos. O sistema imune aviário pode ser estimulado para produzir um repertório de anticorpos de alta qualidade. Nesta revisão apresentamos aspectos gerais do sistema imune aviário enfatizando o IgY e suas aplicações como um imunobiológico.
RESUMO
Com o objetivo de identificar os principais parasitos gastrintestinais que acometem os ovinos, bem como a ocorrência de anticorpos IgG contra Toxoplasma gondii, foram realizados 270 exames coprológicos (OPG/OOPG) e 250 sorológicos (imunofluorescência indireta-IFI) nos ovinos da região de Uberaba-MG. Das amostras de fezes coletadas, 217 (80,37%) eram positivas, com prevalência de Strongyloidea (88,47%), Eimeria spp. (63,13%), Strongyloides sp. (24,42%), Skrjabinema sp. (0,73%) e Moniezia sp. (0,73%) e Capillaria sp. (0,46%). Dos 250 soros testados para Toxoplasma gondii, 144 (57,60%) apresentavam títulos acima do ponto de corte (64), sendo 77,78% com título de 64 e 22,22% de 128. Esses resultados são importantes para nortear proprietários e veterinários sobre a necessidade de diagnosticar e controlar as parasitoses que acometem os rebanhos ovinos.
In order to identify the gastrointestinal sheep´s parasites, and the occurrence of antibodies against Toxoplasma gondii, 270 stool tests (OPG/OOPG) and 250 serological tests (indirect immunofluorescence (IIF) were performed in properties in the region of Uberaba-MG. From the stool samples collected 217 (80.37%) were positive, with a prevalence of Strongyloidea (88.47%), Eimeria spp. (63.13%), Strongyloides sp. (24.42%), Skrjabinema sp. (0.73%), Moniezia (0.73%) and 0.46% Capillaria sp. From the 250 sera tested for Toxoplasma gondii, 144 (57.60%) had titers above the cut-off (64), 77.77% with title 64 and 22.22% with title 128. These results are important to guide owners and veterinarians about the need for prevention and control methods for parasites that affect sheep flocks.