Stiff man syndrome with invasive thymic carcinoma

Stiff man syndrome is a rare disease characterized by painful chronic spasms in the muscle and skeletal system. This syndrome is an autoimmune neurologic disorder which is associated with thymoma. We treated a 32-year-old male patient with a type C thymoma [based on the World Health Organization classification] who had stiff man syndrome. The patient underwent an extended thymectomy which brought about alleviation of his symptoms