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An. bras. dermatol ; 89(6): 878-884, Nov-Dec/2014. tab, graf
Artigo em Inglês | LILACS | ID: lil-727648

RESUMO

BACKGROUND: Masseter hypertrophy has been treated with botulinum toxin injections because of esthetic complaints especially in Asians. OBJECTIVES: The goal of the present study was to evaluate the efficacy of abobotulin toxin use in masseter hipertrophy treatment in Brazilians. METHODS: Ten Brazilian female patients with masseter hypertrophy were subjected to injections of 90U of abobotulinum toxin A applied on each side respecting the safety zone stabilished in literature and were followed up for 24 weeks. RESULTS: When analyzing the coefficients between measures of middle and lower third of the face obtained from standardized photographs, an increase was observed, with statistical significance at 2 weeks (p=0.005) and 12 weeks (p=0.001). The progression of lower third reduction was 3.94%, 5.26%, 11.99%, and 5.47% (2, 4, 12, and 24 weeks respectively). All patients showed improvement in bruxism after treatment. Observed adverse effects were masticatory fatigue, smile limitation, and smile asymmetry. CONCLUSION: The use of abobotulinum toxin A for masseter hypertrophy is effective in Brazilians and reached its maximum effect of facial thinning at 12 weeks. Smile limitation had a higher incidence compared to that reported in the literature and may result from risorius muscle blockage caused by toxin dissemination. Despite its side effects, 80% of the patients would like to repeat the treatment. .


Assuntos
Adulto , Feminino , Humanos , Toxinas Botulínicas Tipo A/uso terapêutico , Hipertrofia/tratamento farmacológico , Músculo Masseter/anormalidades , Músculo Masseter/efeitos dos fármacos , Fármacos Neuromusculares/uso terapêutico , Brasil/etnologia , Face , Injeções Intramusculares , Sorriso/fisiologia , Fatores de Tempo , Resultado do Tratamento
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