Influence of caloric restriction and exercise on mitochondrial quality control in skeletal muscle / 体力科学

Mitochondria play a central role in energy production but also are the main cellular source of reactive oxygen species (ROS). It is widely believed that aging is related to the accumulation of oxidative molecular damage due to ROS. Aging also induces a decrease in muscle function. Recent studies indicate that caloric restriction and physical exercise suppress the decrease in muscle function though the maintaining quality of mitochondria. This review provides the current understanding of the influence of caloric restriction and exercise on mitochondrial quality control in skeletal muscle.

Study for Development of Evaluation System for Atherosclerosis with Fundus Camera in Annual Health Checkups / 日本農村医学会雑誌

[abstract in Japanese]