Screening of some medicinal plants reputed for anthelminthic activity on in vitro test models

Thirty three medicinal plants, traditionally claimed to be useful for purging human intestinal roundworms were evaluated experimentally for their anthelminthic action against Ascaris summ in vitro. On the basis of producing muscle paralysis of the worm within predetermined experimental periods, seventeen of the plants tested were found to possess anthelminthic activity. Urginea indica and Ananas sativa were most effective and a fungus, Hydnum repanda also showed good activity.

Pharmacognostical identification of market pwaygaing leaf

Pwaygaing leaflets sold in the market for its medicinal value as purgative and laxative drug and also as one of the ingredients in many of the traditional medicine formulations (TMFs) was pharmacognostically identified to be Cassia angustifolia Vahl.

Quantitative determination of senna ingredient from Traditional Medicine Formulations TMF-09, TMF-10 and TMF-12

Quantitative determination of a major plant ingredient Senna contained in Myanmar Traditional Medicine formulations (TMFs)- namely TMF-09, TMF-10 and TMF-12 were estimated by following Schedule XIII and XIV of Wallis (1953). Quantitative microscopic work conducted at the Pharmacognosy Laboratory of the Pharmacology Research Division, could quantify the proportion of Senna ingredient, from the above three TMFs.

Bio-availability study of tetracycline

Bio-availability of tetracycline hydrochloride capsules, 500 mg orally administered, was studied on 24 healthy adult Myanmar, aged 16 to 40 years. The peak tetracycline serum concentration of 1.42 0.24 g/ dl was attained in 4 hours, with a gradual fall to 0.16 g/ dl at 24 hours. Myanmar females, when compared to their male counterparts, showed a poorer ability to absorb the drug and had a shorter drug half-life in accordance with their obviously greater drug elimination. Nevertheless there were no significant differences between males and females regarding the remaining major pharmacokinetic parameters such as, the time at which maximum concentration of drug in serum occurred, apparent volume of drug distribution, and systemic blood clearance of the drug. The clinical implication is thus discussed.