A Case of the Juvenile Xanthogranuloma of the Nasal Cavity and Testis / 대한이비인후과학회지

Juvenile xanthogranuloma (JXG) is a benign, normolipaemic, self-healing condition and a type of histiocytosis that occurs most frequently in infants and children, although adults may also be affected. This condition usually presents with a solitary or multiple cutaneous lesions and occasionally with extracutaneous lesions, especially the eye, lung, liver, kidney and pericardium. Histologically, JXG represents an accumulation of histiocytes lacking Birbeck granules (non-Langerhans cell), which can be differentiated from the Langerhans cells by specific staining techniques. The lesions may be excised for diagnostic, cosmetic or symptomatic reasons. We report a case of juvenile xanthogranuloma that occurred in the nasal cavity and testis for the first time.

The Rosai-Dorfman Disease of the Nasal Cavity and Salivary Gland: A Case Report / 대한이비인후과학회지

Rosai-Dorfman disease (RDD), or sinus histiocytosis with massive lymphadenopathy, is a rare idiopathic histiocytosis that most commonly involves the cervical lymph nodes, Extranodal involvement occurs in 30- 40% of cases, most often in the head and neck. Characteristic histological findings include emperiopolesis (intracellular engulfment) of lymphocytes and S-100 protein positivity. Treatment of Rosai-Dorfman disease is unnecessary unless the disorder becomes life-threatening, since the disease will resolve spontaneously in most patients. We experienced a case of extranodal RDD at the nasal cavity as the initial lesion prior its nodal involvement. The patient was a 18-year-old woman who complained of nasal obstruction for 4 years and had a submandibular mass that persisted during the last 3 months. Histologically, all specimens taken from the left nasal cavity, the left submandibular mass and the left upper jugular lymph node showed heavy infiltration of plasma cells, lymphocytes and sheets of macrophages with abundant pale cytoplasm which replaced the existing organ architecture.

Fibromyxoma Arising from the Maxilla: A Case Report / 대한이비인후과학회지

Fibromyxomatous lesions of the maxilla are rare. Although other locations are also uncommon, this tumor can occasionally be found in jawbone. They are slow-growing, which result in expansion of the surrounding bony cortices. Maxillary and man-dibular myxomas are locally aggressive neoplasms that are thought to arise from fibroblasts of the dental papilla or sinonasal mucosa. The precise origin of these tumors, however, remains controversial. When present in the maxilla, they can extend into the maxillary sinus, the nose, or the orbit. The differential diagnosis should be made from neoplasms in which myxomatous change can be a prominent secondary feature such as liposarcomas, chondrosarcomas, and neurofibromas. We report a case with a large maxillary mass occluding the nasal cavity and expanding hard palate and gingivobuccal area. The histopathologic diagnosis was odontogenic fibromyxoma originating from canine tooth. The treatment was medial maxillectomy.

A Model of Human Nose and Paranasal Sinuses for the Study of Sinus Ventilation / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: The pathogenesis of chronic paranasal sinusitis has been gradually clarified, but there have been conflicting arguments on the ventilation of paranasal sinus. The aim of the present study is to establish an objective, quantitative and reproducible method for the investigation of the ventilation of paranasal sinuses. MATERIALS AND METHODS: With the axial images of high resolution computed tomography, a fine model of human paranasal sinus was made. The model was fitted with pressure sensors, and the pressure changes in the nasal cavity, frontal, maxillary and sphenoid sinuses were measured by pressure sensors and digital physiograph during nasopharyngeal respiration. RESULTS: Results demonstrated negative pressures compared to the atmospheric pressure during inspiration and positive pressures during expiration in the sinonasal cavities, and the highest and lowest pressures were measured in the nasal cavity. CONCLUSION: This study introduces another method for the investigation on the sinus ventilation through a model study. And this study model has demonstrated that the ventilation of paranasal sinuses depends on nasal respiration. Furthermore, the method is useful to evaluate the results of nasal and sinus surgeries in the case of an obstructed ostium, deviated septum or hypertrophied turbinates.

A Case of Nasal Endoscopic Removal of Nasocranial Metalic Foreign Body / 대한이비인후과학회지

The penetrating foreign body of skull base can be occasionally life-threatening. However, the severity and extent of these injuries depend upon the inflicting object, the anatomic site involved, and the force of penetration. Penetrating injuries generally result from gunshots and knife stabs. The authors experienced a rare case of penetrated metalic foreign body which remained for about 5 years in the left nasal cavity through cribriform plate to frontal lobe. The nasocranial foreign body was removed successfully through nasal endoscopy without difficulty.