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Hyperuricaemia may be associated with an increased risk of stroke, but updated results from several studies have been inconsistent. The present study aimed to evaluate the relationship between hyperuricaemia & risk of stroke.METHODSThis cross-sectional study was conducted in the Department of General Medicine, GSL Medical College and General Hospital, Rajamahendravaram, with a total of 144 stroke patients. Other risk factors were also noted and serum uric acid (SUA) levels were determined.RESULTSThere was a significant (p<0.05) difference in the mean levels of different categories of age and increased levels of SUA levels in both males and females. There was a significant association between hypertension, diabetes mellitus, dyslipidaemia, CAD, but no significant relationship with (p>0.05) history of cerebrovascular accident (CVA), smoking and alcohol consumption. There was a significant association (p<0.05) between stratified SUA levels (normal and hyperuricaemia) and hypertension, diabetes mellitus, dyslipidaemia, coronary artery disease (CAD) and age, but no significant (p>0.05) association with history of CVA, smoking and alcohol consumption.CONCLUSIONSElevated SUA level is a significant risk factor for stroke. elevated serum uric acid level needs to be interpreted carefully in patients with risk factors for vascular events like hypertension, diabetes mellitus, dyslipidaemia and a history of prior vascular events. The prevalence of hyperuricaemia was found to be high especially in patients in their seventh decade of life and later.
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Introduction: Study was undertaken to note the levels of highsensitive C-reactive protein (hs-CRP), serum uric acid, serummagnesium levels in acute myocardial infarction (MI).Material and methods: This study was conducted in GSLMedical College, study was approved by institutional ethicalcommittee. Participants were recruited by folloing inclusionand exclusion criteria. After getting detailed history ofpatient’s blood samples were taken for hemoglobin, bloodurea, serum creatinine, uric acid, serum electrolytes, hs CRP,serum uric acid, serum Magnesium. All the participants weresubjected to ECG and ECHO cardiography. Fischer’s exactChi square test was to find statistical analysis, P<0.05 wasconsidered as statistically significant.Results: Of the 100 study participants, 39% participants’hs CRP levels were ≤3mg/dl; statistically the differencewas significant. When serum ureic acid considered, 46%patients with uric acid levels were ≤7mg/dl 66% participants’magnesium levels were > 1.4mg/dl; The difference wasstatistically significant.Conclusion: The above findings showed a positive correlationof elevated hs CRP and uric acid; and low magnesium withvarious risk factors of MI.
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Background: In this study, an attempt has been made to find the correlation between Diabetic Retinopathy (DR) and serum magnesium in type 2 Diabetic Mellitus (DM) cases.Methods: Study was conducted in the department of General Medicine, GSL Medical College. Study protocol was approved by institutional ethical committee. All the non-critically ill type 2 DM individuals of all ages attended the outpatient services were included in the study. The reference range of Magnesium was taken as 1.7-2.4 mg/dL. Patients with low and normal Magnesium levels were categorized as cases and controls respectively. Statistical analysis was performed using SPSS software 21, Chi square test was used to compare the different qualitative variables; p<0.05 was considered as statistically significant.Results: A total of 163 individuals were included in the study, the mean age was 55.72 years, ranged between 39 to 75 years; male female ratio was 1.12. DR was diagnosed in 54% cases and low magnesium levels were detected in 40% cases; the difference was statistically not significant (p>0.05).Conclusions: Estimation of glycaemic levels and serum magnesium can help us predict the onset and progression of DR.