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Medical Principles and Practice. 2008; 17 (5): 425-428
em Inglês | IMEMR | ID: emr-89015

RESUMO

To report a patient with coeliac disease [CD] associated with primary biliary cirrhosis [PBC] who presented with myopathy without classical symptoms of CD. Clinical A 42-year-old woman presented with inability to walk and marked loss of motor function. She had elevated liver enzymes with a cholestatic pattern. Antimitochondrial antibody M2 band, anti-endomysial antibody, antigliadin IgA and IgM were positive. Histopathologic findings of the liver revealed PBC and duodenal biopsy was consistent with CD. She was also found to have osteomalacia. She showed slow response to gluten-free diet, but accelerated full recovery with vitamin D replacement. In PBC patients with subclinical CD and myopathy, vitamin D status can provide a basis for treatment


Assuntos
Humanos , Feminino , Doenças Musculares , Doença Celíaca , Cirrose Hepática Biliar , Comorbidade , Vitamina D , Autoanticorpos , Dieta Livre de Glúten , Diarreia , Esteatorreia , Síndromes de Malabsorção
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