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Korean Journal of Medicine ; : 154-158, 2016.
Artigo em Coreano | WPRIM | ID: wpr-65766

RESUMO

Neurofibromatosis type 1 (NF-1) is an autosomal dominant disorder with a prevalence of approximately 1 in 3,500 live births. NF-1 predisposes to various benign and malignant neoplasms. Neurological malignancies are most frequent, but the risks of non-nervous system tumors, such as of the esophagus, stomach, colon, liver, biliary tract, pancreas, lung, melanoma, thyroid gland, female breast and ovaries, are also increased. Malignant tumors are the most common cause of death in patients with NF-1. Cases with double primary tumors have been reported, but cases involving three or more primary cancers are rarely reported. Therefore, we present the case of a NF-1 patient diagnosed with gastrointestinal stromal tumor, breast cancer and ampulla of Vater cancer.


Assuntos
Feminino , Humanos , Ampola Hepatopancreática , Sistema Biliar , Neoplasias da Mama , Mama , Causas de Morte , Colo , Esôfago , Tumores do Estroma Gastrointestinal , Nascido Vivo , Fígado , Pulmão , Melanoma , Neurofibromatoses , Neurofibromatose 1 , Ovário , Pâncreas , Prevalência , Estômago , Glândula Tireoide
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