Breast cancer: genetics, risk factors, molecular pathology and treatment

Breast cancer within incident of one million new cases each year has become one of the most common malignancies and leading cause of death among females. This disease is comprised of about 18% of women cancers. The availability of early detection and improved treatments may decrease the mortality rates which reflected in the United States and many other western countries. Breast cancer in over the past 20 years may also have contributed to the Increasing age, nulliparity, positive family history of breast cancer, and use of menopausal hormone therapy were positively risk factors associated with breast cancer. Therefore, studying this malignity is prominent due to its mortality world wild. Evaluation and study of different aspects of breast cancer have been established during past decays which, in this review, it is presented and discussed

Effect of essential oil of Rosa Damascena on human colon cancer cell line SW742

In this study, we report the effect of the essential oil of Rosa Damascena on human colon cancer cell line [SW742] and human fibroblast cells. Colon cancer is the second most common fatal malignancy. Owing to the existence of many side effects and problems related to common treatments such as surgery, chemotherapy and radiotherapy, alternative treatments are being investigated. Some herbal medicines have shown promising results against different types of cancers. Herbal medicines used have included the use naturally occurring essential oils. The essential oil of Rosa Damascena was obtained by distillation and its effect on SW742 cell-line and fibroblast cells were investigated with cell culture. The cells were cultured and different volumes of essential oil were induced to the cells. After 48h incubation, cell survival was measured and using statistical analysis, the findings were evaluated and reported. This study showed that soluble part of Rosa Damascena oil increases cell proliferation in high volumes and the non-soluble component decreases cell proliferation. The effects of essential oils, such as Rosa Damascena, on cell proliferation require more thorough investigation