RESUMO
Myasthenia gravis, a disease characterized by weakness and easy fatigue of skeletal muscles, has been associated with other diseases of presumed autoimmune nature. These include rheumatoid arthritis, systemic lupus erythematosus, thyroid dysfunction, hematologic disease, gammopathy, infection, cancer, inflammatory myopathy, etc. In some cases of myasthenia gravis, an inflammatory myopathy develops and adds to the weakness already caused by the transmission defect. We report a 31-year-old female who had the manifestations of myasthenia gravis and polymyositis with the brief review of literatures.
Assuntos
Adulto , Feminino , Humanos , Artrite Reumatoide , Fadiga , Doenças Hematológicas , Lúpus Eritematoso Sistêmico , Músculo Esquelético , Miastenia Gravis , Miosite , Polimiosite , Glândula TireoideRESUMO
Miyoshi myopathy is a rare distal myopathy of early adult onset and autosomal recessive inheritance. Weakness usually appears between 15 and 30 years of age starting from the posterior compartment of the legs. Serum creatine kinase (CK) level is characteristically elevated to 10- to 100-fold above the normal range. Muscle biopsy shows myopathic changes without vacuoles consistent with muscular dystrophy. It has not been reported in Korea as yet, so far as we know. We report a 23-year-old female who had the typical manifestations of Miyoshi myopathy with the brief review of literatures.