RESUMO
Polyclonal anti-thymocyte globulin [ATG] is used as an immunosuppressive agent in the treatment of aplastic anemia [AA]. Serum sickness is a recognized side effect of ATG. We observed abnormal skin manifestation in patient with aplastic anemia who had been treated with ATG. We conclude that abnormal immune function caused by aplastic anemia and ATG and corticosteroids may aggravate the signs of serum sickness
Assuntos
Humanos , Masculino , Anemia Aplástica/tratamento farmacológico , Doença do Soro/patologia , Dermatopatias/induzido quimicamente , Doença do Soro/etiologiaRESUMO
Acute renal failure is one of the side effects while using intravenous immunoglobulins. This complication is also observed with iodinated contrast media. Herein, we describe a patient with acute renal failure who received intravenous immunoglobulins and iodinated contrast media concomitantly. Both drugs are responsible for osmotic nephrosis. The same effect on renal cells may explain a synergistic effect on renal function