effect of selenase on the disease process of patients with septic shock admitted to the intensive care unit: a clinical trial in Tehran

Despite discovering new antibiotics, mortality due to septic shock has remained high. This research has examined the effect of selenase in patients with septic shock admitted to the intensive care unit [ICU] of a hospital in Tehran. This double-blind clinical trial was done on 80 participants [40 case and 40 control] who were admitted to the ICU with septic shock. Every participant in the case group was administered 500 micro g selenase twice daily for 10 days. In contrast, each participant of the control group was treated with placebo [normal saline]. Data were collected by observation and recorded in a questionnaire. Chi-square and Student's t-test were used for data analysis. In this study 34 participants [42.5%] were men and 46 [57.5%] were women. The duration stay in the ICU in treatment group was less than in the observation group which was statistically significant [P =.01]. There was also a significant difference regarding the frequency of morbidity and mortality rates between the two groups [P =.03 and P =.02, respectively]. Selenium at a dosage of 500 micro g [twice daily] is effective in those who have suffered from septic shock. Still, more studies are needed to determine the best dosage and administration method of this drug

Antimutagenicity effect of Citrus nobilis

Currently cancer is considered as one of the main factors of mortality globally. Many chemicals in our environment can cause genetic mutations and are potentially responsible for millions of cancer-related deaths. Nowadays the scientists are looking for food materials which can potenthially prevent the cancer occurrence. The purpose of this research is to examine antimutagenicity and anticancer effect of Citrus nobilis .The Citrus nobilis was subsequenthy evaluated in terms of antimutagenicity properties by a standard reverse mutation assay [Ames Test]. This was performed with histidine auxotroph strain of Salmonella typhimurium[TA100] .Thus, it requires histidine from a foreign supply to ensure its growth.The aforementioned strain gives rise to reverted colonies when expose to carcinogen substance [Sodium Azide] . In Ames Test the Citrus nobilis prevented the reverted mutations and the hindrance percent of Citrus nobilis was 72.46% . This is the first study that have revealed antimutagenicity effect of Citrus nobilis

[In-vitro resistance pattern of Escherichia coli isolated from patients with urinary tract infection in Tehran]

Since antibiotical treatment for Urinary Tract Infection should be based on an incident epidemiology and uropathological resistance pattern, this study aims to nominate the sample of active bacteria resistance in Urinary Tract. This descriptive-episodic study has been accomplished in Tehran-Iran in 2013. In this study sensitivity was determined by diffusion disk assay for treatment in Urinary Tract Infection diseases has been taken into account. Demographic and past medical history was collected by a questionnaire. In our study 372 patients include 308 female and 64 males the highest resistance were seen in cotrimoxazol [51.8%] and cephalexin [39%]. The highest sensitivity respectively was seen in using of ciprofloxacin [68%], in pregnant period, the highest sensitivity in using of ciprofloxacin and the highest resistance were seen in cotrimoxazol. In this study was showed E.Coli is the most common microorganism in urinary tract infection

Epidemiologic profile of shigellosis among Iranian military personnel: a retrospective study in the army

To assess the epidemiologic features of shigellosis in Iranian military personnel of the Army. The data was gathered from archived reports of Iran's Army at AJA University of Medical Sciences. All military personnel with confirmed diagnosis of shigellosis reported by the Army physicians were included in the study. Data analysis was done by appropriate statistical functions using STATA software. In a 7-year period [2005-2011] the total number of cases was 1710 from 25 provinces of Iran. A large difference was found out in the incidence rates of different provinces. 69% of all cases were from the five provinces of Hormozgan, Khuzestan, Sistan-Baluchistan, Bushehr and Guilan. Although the majority [55%] of the cases had occurred in spring, the association between season and incidence rate was not significant [P = .08]. Among the three studied forces 45% of reported patients were from Navy. The overall occurrence of shigellosis has decreased among Iranian army personnel from 2005 to 2011, but the incidence is still high enough to be considered as a major problem. Army healthcare commanders are expected to improve necessary facilities, especially in the Navy and in endemic provinces, to decrease the transmission of this infection.

Newly detected hypertension in an Iranian population: an epidemiological study

Background: Early detection of undiagnosed hypertension may prevent or reduce the onset and progression of many diseases.Objective: To investigate the prevalence of undiagnosed hypertension in an Iranian population and its relation with socio-demographic, anthropometric, and biochemical factors.Methods: Four thousand five hundred nineteen subjects, aged 15-65 years, were eligible for the study. They were entered into the study through the cluster sampling method.Results: The overall prevalence of previously unknown hypertension was 24.2%. It was higher among urban dwellers who were poorly educated, married, and were manual laborers by occupation compared to other groups.Conclusion: Poor literacy status as well socioeconomic conditions may be positively associated with hypertension. Undiagnosed hypertension can be lowered by increasing access to routine blood pressure measurement, pre-employment medical examination, and improvement of the health seeking behavior in these groups.

[Effect of school- based education program about HIV/AIDS on the knowledge of students]

The aim of this study was to determine the effect of a school- based educational program regarding HIV/AIDS and the knowledge held by the high school students. This quasi-experimental study was conducted with 230 high school students [grade 10-12; female, male]. Teaching aids used for this intervention was a combination of three methods including lectures, showing an educational movie and pamphlets that encompassed a total of 90 minutes. There was a significant difference between the student's knowledge regarding HIV/AIDS before and after this type of intervention