RESUMO
In recent years the emergence of antibiotic resistance has a high prevalence, so that it has become one of the complexities in modern medicine. This study was performed with the aim of evaluating the bacteria isolated from clinical samples of the patients with various infections and estimating the prevalence of various bacteria and also antibiotic resistance pattern. At first, culture was prepared from wounds of the patients with nosocomial infection in Imam Khomeini and Burn hospitals in 2008-2009. Then, after isolation of bacteria, antibiotic susceptibility was determined using antibiotic discs. Data were analyzed using statistical tests [ratio] at the significance level of p = 0.05. Levels of antibiotic resistance and susceptibility in microorganisms isolated from 403 various samples included: Pneumococcus [2.2%], coagulase-positive [4%] and coagulasenegative [21.3%] Staphylococci, Pseudomonas [18.9%], Klebsiella [25.6%], Escherichia coli [26.8%], Shigella [1%], and proteus [0.2%]. Among them, isolated klebsiellas showed various susceptibilities to different antibiotics. The most resistance was obsereved in coagulase-positive Staphylococci to cloxacillin, so that 80% of coagulase-positive Staphylococci were resistant to cloxacillin. Based on the results of this study, and considering the possibility of transferring resistance genes to other bacteria, it is necessary that health care authorities pay more attention to planning, monitoring of control of nosocomial infections, and application of appropriate and effective treatment protocols in order to elimination of multidrug resistant microorganism. Also, limitation of the prescription of multidrug resistant antibiotics seems to be of main requirements of treatment protocols.
RESUMO
Despite the advances in medical technology has resulted in decrease of occurrence of infectious disease, tuberculosis is still the most common cause of mortality. Prisoners are at high risk of acquiring TB. The most common reasons are overcrowding, malnutrition, high-risk behaviors, addiction and HIV infection. In current study, the epidemiology and prevalence of TB in prisons in Iran was investigated. Checklists were obtained prisons throughout of iran from and data were then analyzed to determine the prevalence of TB among the prisoners. In this study, 339 patients were diagnosed with TB. All patients were older than 15 years. All except two patients were male. In 83 cases, TB infection is along with HIV. Because of unfavorable environment of prison the level of TB in prisons is higher than that of the civilian population. Additionally high levels of MDR-TB in prisons have been reported from some studies. The results obtained from current study indicated the prevalence of TB also is high in Iranian prisons and in 83 persons it was along with HIV infection which can make difficulty in treatment and increase the risk of MDR. These results show the important role of control and treatment of TB in prisons