RESUMO
Background: Tuberculosis is still common in developing countries, and sometimes involves central nervous system, proper diagnosis and early treatment effectively reduces the mortality and morbidity associated with this disease
Objective: Observe presenting symptoms and outcome on anti-tuberculosis drug treatment
Material and Methods: This prospective study was conducted in the Department of Neurosurgery in collaboration with Department of Pathology, Ayub Teaching Hospital Abbottabad from March 2010 to December 2016. 22 patients; 8 females and 14 males were studied for their signs and symptoms and outcome after anti-tuberculosis drug treatment
Results: The most common location of tuberculous lesions was supratentorium [81%] particularly in parietal lobe [50%] followed by frontal lobe [22.7%] and occipital lobe [18.2%]. 45% patients had prior history of tuberculosis. Headache was the predominant complaint [72.7%] followed by altered sensorium [31%], seizures [27.3%] and cranial nerve palsies [22.7%]. After 12 months of anti-tuberculosis treatment ATT, about 87% of patients had either resolved or regressed tuberculoma
Conclusion: Brain tuberculomas are benign lesions with" malignant" behavior. Early diagnosis and anti-tuberculosis drug treatment can effectively treat this lesion forever. So in developing countries like Pakistan, when there is cystic, nodular or multiple lesions, there should be suspicion for brain tuberculoma and work up should be done because of very good prognosis associated with anti-tuberculosis drug treatment
RESUMO
To study the spectrum of inflammatory and developmental odontogenic cysts. Epithelial lined cysts of the oral cavity are among the most commonly encountered oral diseases from both the clinicians and pathologists perspective. To reach a specific diagnosis a multi team approach is necessary which includes radiologists, surgeons and pathologists. Two major categories of cysts exist; odontogenic and non-odontogenic. The most commonly encountered odontogenic cysts are radicular or periapical cyst; which may occur in any age group but common in 3[rd] and 4[th] decade. The second common type is dentigerous cyst that accounts for 17% of all the odontogenic cysts. Keratocysts account for 10% of all odontogenic cyst and can have more chances of recurrence. 60 cases sent to the Pathology Department during Sept. 2006 to Dec 2009 were included in the study, after observing inclusion and exclusion criteria. After gross examination the sections were routinely processed and slides stained with Hand E. All the slides were thoroughly examined by two consultant histopathologists and postgraduate pathology resident. 50% were radicular cysts, 36% were dentigerous cysts, keratocysts and eruption cysts accounted for 8% and 5% respectively. In one case of dentigerous cyst ameloblastoma was diagnosed and one case was diagnosed at maxillary antrum, an unusual site for dentigerous cysts