Effects of fresh mineralized dentin and cementum on socket healing: a preliminary study in dogs

OBJECTIVES: Dentin is composed of many minerals and growth factors. Based on this composition, we studied its effect as a possible regenerative material for alveolar healing. MATERIALS AND METHODS: This study was conducted using four 2.5-year-old mongrel dogs (male; weight, 25 to 30 kg). The third mandibular premolars were carefully mobilized with a dental elevator and then removed using forceps. The crown portions of the extracted teeth were removed with cutters, and the root portions of the remaining teeth were collectively trimmed as closely as possible to 350 to 500 microm. Dentin and cementum (DC) chips harvested from the extracted teeth were soaked in blood and packed into the fresh sockets (autograft). Biopsies were performed at the ends of day 14 and day 56 following implantation. Data were expressed as mean+/-standard deviation and compared with t-test results. RESULTS: The ratio of SA(bone) to total area of each probe was determined and was 170+/-16 microm2 for the control group and 71+/-14 microm2 for the DC group, a significant difference (P<0.05). CONCLUSION: DC particulate grafts offered no improvement in bone regeneration in alveolar extraction sockets.

Multiple absences of the branches of abdominal aorta with congenital absence of the portal vein, unilateral adrenal agenesis and persistent ductus arteriosus in a female cadaver / 대한해부학회지

We report on an extremely rare case of multiple absences of the branches of abdominal aorta with congenital absence of the portal vein, unilateral adrenal agenesis and persistent ductus arteriosus in an adult female cadaver. Specifically, instead of celiac trunk, superior and inferior mesenteric arteries, solely a single arterial trunk aroused from the anterior aspect of abdominal aorta, inferior phrenic and ovarian arteries were absent in both sides. Left kidneys drained by two veins. There were not superior, splenic and mesenteric veins, while left renal vein received an additional vein, which run downward and drained primarily all parts of digestive tract and its associated glands (portal vein did not exist). Right adrenal gland was absent. To the best of our knowledge, it is the only reported case with such widespread anomalies. We think the importance of this case is beyond the surgical consideration and needs more profound developmental studies.