FNAC and core needle biopsy - A comparison in space occupying lesions of liver

A prospective analysis was conducted on 110 FNAC and results were compared with histologicul reports of patients with intrahepatic focal defects. Cytology permitted a diagnosis of the lesion in 98% cases. When aspirates with insufficient material were excluded [4], the diagnostic accuracy of FNA was 94%. Among the 106 patients who underwent both procedures, FNAC and CNB had the some diagnostic accuracy 94% i.e., sensitivity 96% and specificity 93% of FNAC. There were no complications during the execution of FNAC and CNB. FNAC is an effective and safe method in the diagnosis of focal hepatic lesions, with diagnostic accuracy almost similar to that of CNB. When the two techniques are combined, the accuracy of the diagnosis of malignancy of focal liver lesions increases

Neonatal intestinal perforation secondary to congenital segmental agenesis of intestinal muscularis

Congenital segmental absence of intestinal musculature is a rare disorder of unknown etiology. It is a rare cause of intestinal obstruction or perforation in newborns which may resemble necrotizing enterocolitis [NEC]. The diagnosis is confirmed histologically by segmental absence of the muscularis propria, normal intact mucosa, submucosa and serosa. The absence of inflammation, hemorrhage and necrosis helps to distinguish it from NEC. A case of an infant boy with intestinal perforation secondary to segmental absence of intestinal musculature is presented, the literature is reviewed and possible etiologies are discussed