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Objective To evaluate the relationship between subventricular zone(SVZ), the shortest distance from tumor centroid to the edge of the lateral ventricles (TV) and prognosis of patients with glioblastoma multiforme (GBM). Methods The clinical data of 130 patients with GBM in our hospital since 2006 to 2016 were retrospectively reviewed and 45 persons of these patients with SVZ were involved. Chi-square test and survival analysis was performed to identify prognostic factors associated with GBM. Results Chi-square test indicated that there were no significant differences in the distribution of age, gender, tumor location, tumor volume, preoperative epilepsy and the extent of resection in these two groups with involvement of SVZ or not (P>0.05). Similarly, there were no statistically significant differences in the distribution of age and sex, tumor location, tumor size, preoperative epilepsy between TV0.05). Univariate analysis showed that adjuvant therapy (HR=0.765, 95%CI:0.557-0.998, P=0.045), SVZ (HR=2.996, 95%CI:1.995-4.500, P0.05). When the parameters with statistical significance identified by univariate analysis were included in the multivariate analysis, the results showed that adjuvant therapy (HR=0.540, 95%CI:0.333-0.875, P=0.012), SVZ (HR=2.634, 95%CI:1.725-4.022, P0.05). When the parameters with statistical significance identified by univariate analysis were included in the multivariate analysis, the results showed that adjuvant therapy (HR=0.726, 95%CI:0.529-0.997, P=0.048) and TV(HR = 3.234, 95%CI: 1.711- 6.112, P<0.01) was independent prognostic indicator in patients of GBM with SVZ involvement (P<0.05). Conclusions Involvements of SVZ and TV less than 30 mm are the risk factors for the prognosis of patients with GBM.
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Objective To evaluate the barium meal radiography and CT scans in diagnosing malignant gastrointestinal stromal tumors (GIST) of small intestine. Methods The clinical and imaging data of 16 patients with GISTs of small intestine which were diagnosed surgically and pathologically were analyzed and summarized. In this group CT scan and gastrointestinal barium exam(GI) was performed. Results The tumors included 6 low-malignant GISTs of small intestine and 10 high-malignants. The diameter varied from 3.2 cm to 7.2 cm, the average size was 5.6 cm. The main signs of barium meal of malignant GIST of small intestine included flattened or destroyed mucosa runae, partial lumen stenosis, and barium fleck and fistula in the tumor. On CT scans, the main manifestation was an extraluminal mass with multiple necrosis areas of low density. Conclusion Barium examination and helical CT scan are the major imaging techniques in the determination of the location of GIST of small intestine. The appearance of imperfect lumen and the irregular tumor with multiulcerations or low density regions and inhomoneneous enhancement may lead to the correct diagnosis of malignant GIST.