Hydatid cyst of unusual sites, an experience at Chandka medical college Larkana

Hydatid cyst occurs throughout world but more in endemic areas where human beings live in close contact with cattle and dogs. Common organs affected by hydatid cyst are liver and lung but rarely occurs in other organs as well. To evaluate the unusual sites of hydatid cyst in human beings, this will help the clinicians in early diagnosis and management. Observational. The study was conducted in the Department of Pathology, Chandka Medical College Larkana from January 1995 to December 2009. Total of 191 patients, admitted in various hospitals of Larkana, and operated for hydatid cyst or incidental findings at hisptopatholgical examination were included. All the fixed biopsies were cut into representative tissue blocks, processed, stained for haematoxylin and eosin and examined under light microscope. Total of 191 cases of hydatid cyst were received in 15 years, out of which 119 [62.3%] cases occurred in liver with mean age 41.27 years +/- 16.27 SD, 44 [23%] in lung with mean age 44.04 +/- 15.81 SD and remaining 28 [14.7%] in other uncommon organs. The presence of hydatid cyst in uncommon sites in Larkana is 14.7%, hence possibility of hydatid cyst in almost every organ of the body should be suspected

Low dose, short term, triple therapy for helicobacter pylori associated peptic ulcer

To confirm the efficacy and tolerability of a new, low-dose, short-term triple therapy, 31 endoscopically diagnosed cases of peptic ulcer who were helicobacter pylori positive by brush cytology and urease test were inducted into the study. These patients were given lansoprazole 30 mg once a day, clarithromycin 250 mg twice a day and tinidazole 500 mg twice a day for one week only. Endoscopy, urease test and methylene blue test for helicobacter pylori were repeated four weeks after stopping the therapy. Ulcer healed in all the patients while helicobacter was eradicated in 90.3% of patients