Role of Intraperitoneal Antibiotic Lavage in Peritonitis

Although mortality and morbidity associated with generalized peritonitis has been brought down markedly, postoperative complications like wound sepsis, intra-abdomlnal collections, paralytic ileus and septicemia do occur in some cases. To minimize such complications different measures have been tried so far, including intraperitoneal lavage with saline solutions and antibiotics. We conducted a study involving fifty patients over a period of two years using the third generation cephalosporin, cefotaxime intraperitoneally with encouraging results.