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Artigo em Chinês | WPRIM | ID: wpr-278155

RESUMO

<p><b>OBJECTIVE</b>To identify and assess multiple human papillomavirus types in condyloma acuminatum lesions from patients with genital warts in Beijing area, and compare different features between otherwise healthy and immunosuppressed patients.</p><p><b>METHODS</b>PCR, RFLP and nucleotide sequencing analysis were used to determine HPV types from individual lesions.</p><p><b>RESULTS</b>The predominant type from other healthy patients was HPV6, secondly HPV11. The mean age of patients infected by HPV6 was lower than that of HPV11 and HPV6 + 11. While lesions from immunosuppressed patients were often contained HPV11 or mixed with HPV6. Besides, HPV types 16 and 53 were detected from infected lesions than other HPV types.</p><p><b>CONCLUSIONS</b>HPV6 was the major pathogen of condyloma acuminatum, but infected patients were at lower ages. While HPV11 was most often detected from immunosuppressed patients. As a low risk virus in normal genital tract, HPV53 also could be a pathogen in genital warts.</p>


Assuntos
Adulto , Feminino , Humanos , Masculino , Condiloma Acuminado , Virologia , Papillomaviridae , Classificação , Infecções por Papillomavirus , Infecções Tumorais por Vírus , Verrugas , Virologia
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