Effect of Replacement of New Reverse Osmosis Film of Water Purification System to Clinical Biochemistry / 现代检验医学杂志

Objective To test if the quality of produced water could come up to the standards of clinical biochemistry,and e-valuate the effect of the produced water after replacement of a new reverse osmosis film of the laboratory water purification system.Methods The ion concentration of the produced water was tested by ohmmeter in Beckman Coulter supporting TianChuang water purification system TCHS-RO/100A and HM COM-100 conductivity meter.The biochemical index ALT,AST,TBIL,ALP,GGT,TP,ALB,BUN,CR,UA,GLU,TC,TG,HDL,LDL,CK,LDH,P,Ca of mixed serum were tested 20 times by AU680 under the condition of normal purified water(control group),and the same operation were repeat-ed after changing to newly produced water(experimental group)to evaluate the effect of newly produced water to biochemi-cal analysis.The triglyceride (TG)reagent blank was tested 3times/d for 5 days to evaluate the glycerin level in the pro-duced water.Results The conductivity of purified water was reduced to (0.1±0.0)μS/cm 30 min after starting up by HM COM-100,and the electric resistance of purified water remained stable at 18.25MΩcm 50min after starting up.During the bi-ochemical analysis by AU680,the value of TG in control group=1.04 mmol/L,in experimental group=21.39 mmol/L,the differences showed statistical significance (P0.05).The reagent blank was stable at A660nm=0.015 6±0.000 4 in the fifth day.Conclusion After produced approximately 2 800 L purified water in the system,glycerine could be cleaned up in produced water.It is needed to continuously test the quality of produced water to evaluate the effect of which to clinical bio-chemistry after replacement of a new reverse osmosis film.

Pathogenic culture and detection of antimicrobial resistance of pathogens before and after debridement in patients with open fractures / 中国感染控制杂志

Objective To realize the detection of pathogens and antimicrobial resistance of pathogens isolated from wound secretion in patients with open fractures,so as to guide clinical treatment.Methods 1 472 patients with open fractures from May 2012 to July 2013 were selected from a hospital,pathogens from wound secretions before and after debridement were identified and performed antimicrobial susceptibility testing.Results Before debride-ment,1 246 of 1 472 patients (84.65%)were isolated 2 246 bacterial strains,824 (55.98%)of patients were isola-ted at least 2 kinds of bacteria.Eight hours after debridement,201 pathogenic bacteria were isolated from 195 pa-tients (13.25%).The more serious of Gustilo type,the higher the positive rate of bacterial culture.Positive rate of wound culture were all >50% in patients of all Gustilo types before debridement;positive rate were all 75%.Acinetobacter baumannii had higher resistance to multiple antimicrobial agents,to cefoperazone/sulbactam was 20%;Pseudomonas aeruginosa to imipenem was 10.80%, sensitivity to cefoperazone/sulbactam,cefepime and ceftazidime were all higher.Conclusion For patients with open fractures,timely debridement can reduce wound pathogen,antimicrobial susceptibility testing result is helpful for guiding rational antimicrobial use.

Focus of International Classification of Diseases in China based on key-words co-occurrence method / 中华医学科研管理杂志

The purpose of this article was to explore the hotspots in the field of international classification of diseases in China.The methods adopted were Factor Analysis,Cluster Analysis,Multidimensional Scaling Analysis and Social Network Analysis by building the high-frequency keywords co-occurrence matrix in this field.The themes are clustered into ten classes based on the results of Factor Analysis with ten common factors extracted.The results of Social Network Analysis showed that the research of medical payment methods using medical records information is the core theme in this field,which will continue in the future.

Social Network Analysis of the Co-authoring Network in Domestic International Classification of Diseases Field / 中华医学科研管理杂志

Objective The purpose of this article is to analyze the domestic situation of co-authorship in the field of international classification of diseases using Social Network Analysis.Methods Using UCINET to do this research from the following five perspectives,namely density,degree centrality,betweenness centrality,closeness and subgroup analysis.Results The density of co-authoring network is 0.0021.The number of nodes which made up the main component accounts for 3.46％ of the total nodes.Lin Jie-zhong possesses the highest value of degree centrality,and Guo Yun-qing's value of betweenness centrality and closeness is the highest.Forty-four 2-plexes are found in all authors.Conclusions Currently,the co-authorship is not close,but to a certain extent,the authors liked Lin Jie-zhong,Liang Yao,Li Jian-wei,Fan Wei,Guo Yun-qing,Liu Ai-min and so on constitute the core members or leaders.From the overall point of view,the authors in this field have not yet formed a subgroup phenomenon obviously.The structure of this co-authoring network is loose and isolated.