RESUMO
Objective To investigate the correlation between serum lipids, apolipoprotein and breast cancer. Methods A survey on the prevalence of breast cancer was conducted in out hospital from March 2012 to March 2014. The data of 82 subjects with histologically confirmed breast cancer and 80 healthy control subjects were analyzed. Serum TC, TG, Apo-A, Apo-B, HDL-C, LDL-C were tested at the same time. The grouped according to tumor size, lymph node metastasis, the degree of tissue differentiation, measured values were compared. Results The levels of serum TC,TG, LDL-C, Apo-B in the breast cancer group were (6.20±0.24) mmol/L, (2.45±0.12) mmol/L, (4.58±0.20) mmol/L, (1.25±0.15)g/L respectively, while those in the control group were (4.00±0.20) mmol/L, (0.67±0.17) mmol/L, (2.14±0.22) mmol/L, (0.86±0.24) g/L respectively.All above parameters of the breast cancer group were significantly higher than those in the control group (P<0.05). The levels of serum HDL-C, Apo-A in the breast cancer group were (0.90±0.11) mmol/L and (1.20±0.22) g/L, and those in the control group were (1.98±0.21) mmol/L and (1.36±0.20) g/L, which was signifi-cantly lower than that of the control group (P<0.05). The serum TC level were significantly higher in the lump≥2 cm group than that of < 2 cm group (P<0.05). There was not significant difference between patients with lymph node metastasis and non-metastasis for the levels of serum TC, TG, HDL-C, LDL-C, Apo-A and Apo-B. The levels of serum TG in the breast cancer poorly differentiated group were higher than those in the well differentiated group (P<0.05). And in the well differentiated group, but the serum HDL-C, Apo-A were significantly lower than in poorly differentiated group, the differences were statistically significant (P<0.05). Conclusion Abnormal elevated of the serum TC, TG, LDL-C, Apo B and HDL-C, Apo-A decline is related to the tumors accruing and development of breast cancer.
RESUMO
Objective To explore appropriate surgical procedures for differentiated thyroid carcinoma. Methods Clinical data of 42 patients who received surgery for differentiated thyroid carcinoma from March 2011 to March 2014 in the department of general surgery in our hospital were retrospectively analyzed. Results Among the 42 patients, 40 patients were papillary thyroid carcinoma and 2 patients were follicular thyroid carcinoma; 26 patients received total thyroidectomy, 12 patients received resection of thyroid lobes+isthmus in affected side+near total thyroidectomy in opposite side, and 4 patients received resection of thyroid lobes+isthmus in affected side.19 patients received lymph node dissection of central group, and 9 patients received selective lymph node dissection. 7 patients showed temporary hoarseness after the surgery; 10 patients showed temporary hypocalcemia. Conclusion As for differentiated thyroid carcinoma, clinical classification, clinical staging and results of rapid pathological examination of frozen sections dur-ing the surgery are considered as proofs for comprehensive decision of surgical procedures. Total thy-roidectomy and near-total thyroidectomy are suggested, and neck lymph node dissection is carried out ap-propriately.