The Association between Sleep Duration and Hypertension in Non-obese Premenopausal Women in Korea / 가정의학회지

BACKGROUND: Previous studies have revealed that sleep duration is linked to both obesity and hypertension. Here, we evaluated the association between sleep duration and hypertension in obese and non-obese premenopausal women using representative national survey data from the Korean population. METHODS: A total of 4,748 subjects over 20 years of age from the Korean National Health and Nutrition Examination Survey from 2010 to 2012 were included. To control for risk factors, multivariable logistic regression was used to calculate the adjusted odds ratios and 95% confidence intervals of hypertension across the following sleep duration categories: 8 h/d. RESULTS: Among the participants, 367 subjects (7.7%) had hypertension. Their mean sleep duration was 7 hours. In the non-obese subjects, after controlling for potential confounding variables, the odds ratio for hypertension was 1.86 fold greater in those with a sleep duration of <6 hours (odds ratio, 1.79; 95% confidence interval, 1.05 to 3.03) as compared to those who slept for 6.8 hours. However, there was no association between sleep duration and the risk of hypertension in obese subjects. Long sleep duration (over 8 h/d) was not associated with hypertension in either the non-obese or the obese subjects in this study. CONCLUSION: Short sleep duration (less than 6 h/d) may be a significant risk factor for hypertension in non-obese premenopausal women. However, there is no association between sleep duration and the risk of hypertension in obese women.

Association between Actual or Perceptional Weight Status and Mental Health Issues in Adolescents in Korea

BACKGROUND: Mental health issues in adolescents have recently emerged as a social concern. Previous studies reported that there was a relationship between body image perception and mental health. The purpose of this study was to determine the correlations between actual or perceptional weight status and mental health issues in adolescents in Korea. METHODS: Data was based on the 5th National Health and Nutrition Examination Survey Data (2010-2012). The subjects were 1989 adolescents aged 12 to 18 years. Depending on the actual or perceptional weight status, participants were divided into several groups. Mental health indicators included experiencing stress, depressed mood and suicidal ideation. RESULTS: The multiple logistic regression analysis was conducted controlling for age, abdominal obesity, smoking and alcohol use, potency of exercises, and household income. Although this study did not find a correlation between actual weight status and mental health variables, it did find that girls who perceived themselves as overweight were more likely to experience stress (odds ratio, 2.24; 95% CI, 1.41-3.56) and depressed mood (odds ratio, 1.91; 95% CI, 1.01-3.62). CONCLUSIONS: Adolescent females in Korea who perceived themselves as overweight experienced significantly more stress and depressed mood.

Nonalcoholic Fatty Liver Disease as a Risk Factor for Cardiovascular Disease: Using the Estimation of Framingham Risk Score and Carotid Artherosclerosis

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is known to be associated with obesity, type 2 diabetes, and dyslipidemia and highly related to metabolic syndrome. The purpose of this study was to examine NAFLD as a risk factor for cardiovascular disease using the Framingham risk score and carotid intima media thickness. METHODS: We examined 189 Korean adults older than 20 years who participated in a health screening test and had both carotid and abdominal ultrasounds. Patients with viral hepatitis and history of cardiovascular disease and alcohol consumption (>20 g/day) were excluded. We compared clinical characteristics, the Framingham risk scores, and carotid intima media thickness according to the presence of nonalcoholic fatty liver disease. RESULTS: Framingham risk scores and the estimated 10-year risk for coronary heart disease were higher in subjects with NAFLD (11.5+/-4.7 vs 10.2+/-4.3 P=0.04, 8.7+/-7.3% vs 4.9+/-5.0% P<0.001). Carotid intima media thickness was higher in subjects with NAFLD (0.72+/-0.18 mm) compared to the controls (0.63+/-0.15 mm) (P<0.001). This result persisted significantly after adjusting for age, sex, and the 5 components of metabolic syndrome. Multiple logistic regression analysis showed that the presence of NAFLD (odds ratio [OR], 2.95; 95% confidence interval [CI], 1.495-5.812) and triglyceride level (OR, 2.06; 95% CI, 1.041-4.066) were independently related with carotid atherosclerosis. CONCLUSIONS: These results suggest that NAFLD is a risk factor for cardiovascular disease. Physicians should be mindful of this association when seeing patients with NAFLD.

Nonalcoholic Fatty Liver Disease as a Risk Factor for Cardiovascular Disease: Using the Estimation of Framingham Risk Score and Carotid Artherosclerosis

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is known to be associated with obesity, type 2 diabetes, and dyslipidemia and highly related to metabolic syndrome. The purpose of this study was to examine NAFLD as a risk factor for cardiovascular disease using the Framingham risk score and carotid intima media thickness. METHODS: We examined 189 Korean adults older than 20 years who participated in a health screening test and had both carotid and abdominal ultrasounds. Patients with viral hepatitis and history of cardiovascular disease and alcohol consumption (>20 g/day) were excluded. We compared clinical characteristics, the Framingham risk scores, and carotid intima media thickness according to the presence of nonalcoholic fatty liver disease. RESULTS: Framingham risk scores and the estimated 10-year risk for coronary heart disease were higher in subjects with NAFLD (11.5+/-4.7 vs 10.2+/-4.3 P=0.04, 8.7+/-7.3% vs 4.9+/-5.0% P<0.001). Carotid intima media thickness was higher in subjects with NAFLD (0.72+/-0.18 mm) compared to the controls (0.63+/-0.15 mm) (P<0.001). This result persisted significantly after adjusting for age, sex, and the 5 components of metabolic syndrome. Multiple logistic regression analysis showed that the presence of NAFLD (odds ratio [OR], 2.95; 95% confidence interval [CI], 1.495-5.812) and triglyceride level (OR, 2.06; 95% CI, 1.041-4.066) were independently related with carotid atherosclerosis. CONCLUSIONS: These results suggest that NAFLD is a risk factor for cardiovascular disease. Physicians should be mindful of this association when seeing patients with NAFLD.