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Journal of Clinical Otorhinolaryngology Head and Neck Surgery ; (24): 840-847, 2011.
Artigo em Chinês | WPRIM | ID: wpr-748044

RESUMO

OBJECTIVE@#To explore the expression of MEF2D in NPC tissues, study the relationship between the expression and prognostic.@*METHOD@#Specimens from 101 NPC patients who were follow-up visited 1 to 7 years were analyzed for MEF2D by using immunohistochemistry.@*RESULT@#(1) The expression of MEF2D was higher in the higher clinical stage. (2) Density and Grey of MEF2D was negative correlated (|r| = 0.865, P < 0.01). (3) NPC patients' survival rate after therapies was 52.5%, the survival curve of 1th clinical stage was higher than 4th. (4) The survival curves of MEF2D stages were no statistical significance.@*CONCLUSION@#There's statistical significance of the MEF2D expression in clinical stages, but not in survival curve, which indicated that MEF2D concerned with invasion and metastatic of NPC.


Assuntos
Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Carcinoma , Carcinoma de Células Escamosas , Metabolismo , Patologia , Metástase Linfática , Proteínas de Domínio MADS , Metabolismo , Fatores de Transcrição MEF2 , Fatores de Regulação Miogênica , Metabolismo , Carcinoma Nasofaríngeo , Neoplasias Nasofaríngeas , Metabolismo , Patologia , Estadiamento de Neoplasias , Prognóstico
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