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Objective To explore the diagnosis and treatment of penile verrucous carcinoma,a distinctive variant of squamous cell carcinoma. Methods The clinical data of 8 patients (mean age,46 years) with penile verrucous carcinoma were analyzed retrospectively.All the tumors showed exophytic,papillary lesions,ranging from 2 to 6 cm in the greatest dimension.The tumors were located at glans in 5 patients and invaded to shafts in the other 3.The diagnosis was established by biopsy of the lesion.Three patients with tumor invading to shafts and 1 patient with large tumor at glans underwent partial penectomy, while the other 4 with the tumors localized at glans were treated by local excision. Results Histopathologic examination of the specimens confirmed tumors-free surgical margins in all the cases.The tumor cells were mostly well-differentiated.Fourteen months postoperatively,local recurrence occurred in 1 patient with local excision and partial penectomy was performed; postoperative follow-up of 9 years showed no recurrence and metastasis. During a follow-up of 4 to 13 years,the other 7 patients were disease-free.The patients with local excision of the tumors reported satisfaction of their sexual lives. Conclusions Verrucous carcinoma of penis is characterized by slow growth and a locally aggressive nature.It seldom develops metastasis to regional lymph nodes or distant areas.The prognosis is favorable after appropriate treatment.
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PURPOSETo introduce how to reconstruct defects after resection for locally advanced carcinoma of externa-lia in man. METHODS In 11 male patients after radical resection of the primary lesion and clearance of lymph nodes, fascial flap, rectus abdominis myocutaneous flap or combined myocutaneous flap of musculus gluteus max-imus and musculus tensor fasciae latae are used to reconstruct the large defects. Reconstruction with rectus abdominis myocutaneous flap is explained in detail. RESULTS In 11 male patients. 10 were healed by first intention, one was healed by granulation. CONCLUSION The key to successful operation is to select the suitable myocutaneous flap according to the degree of defects. Indication and key points of the operation are explained.