RESUMO
Objective: to detect the impact of acne vulgaris on quality of life and assess correlation between disease severity, complications and decreased life quality
Methods: this cross-sectional study of one-year duration involving acne patients of 18-30 years was carried out after institutional Ethics Committee clearance. After written informed consent, patients filled a proforma including demographic data, treatment and previous psychiatric history. Clinical grade of acne and severity of pigmentation and scarring were noted. Acne severity was classified as mild, moderate or severe and DLQI was noted. Statistical analysis was performed with the Statistical Package for the Social Sciences [SPSS version 15.0], Chi-square test and Pearson's correlation coefficient
Results: overall mean DLQI was 7.84 [females 8.02, males 7.82] showing no significant difference between the genders. There was no association seen between DLQI scores severity and complications like pigmentation [p=0.198] and scarring [p=0.095]. There was significant association between severity of acne grades and DLQI scores [p=0.014]
Limitation: the study population was restricted to patients visiting our outpatient department. Only DLQI questionnaire was used for evaluation, which could detect psychosocial problems, but not depression or anxiety without clinical assessment
Conclusion: our study confirms a negative impact of acne on quality of life substantiating a holistic approach treating physique and psyche for well-being of the person
RESUMO
Leprosy can infect many tissues besides peripheral nerves and skin. Mycobacterium leprae can occasionally invade blood stream. Objectives The aim of the study was to determine the frequency of bacteremia in leprosy patients. Buffy coat smears and smears from peripheral blood samples and slit-skin smears of 20 patients with Hansen`s disease [6 with lepromatous, 8 with borderline lepromatous, and 3 each with borderline tuberculoid and pure neuritic leprosy] were stained with Ziehl-Neelsen method for acid-fast bacilli. Out of 20 patients, slit-skin smears were positive in 10 patients [5 each with lepromatous and borderline lepromatous leprosy] while buffy coat smears and blood smears were positive in 2 and 1 patients of lepromatous leprosy, respectively. Bacteremia rarely occurs in leprosy