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1.
Chinese Journal of Contemporary Pediatrics ; (12): 81-85, 2024.
Artigo em Chinês | WPRIM | ID: wpr-1009897

RESUMO

Neonatal lupus erythematosus (NLE) is caused by the transmission of maternal anti-Ro/SSA antibodies, anti-La/SSB antibodies, and other autoantibodies to the fetus through the placenta. Usually, with the disappearance of autoantibodies in the children's body, abnormal changes in the mucocutaneous, blood system, and digestive system can spontaneously subside, but the damage to various systems caused by autoantibodies may persist for a long time. This article provides a comprehensive review of the manifestations and prognosis of NLE in various systems, including mucocutaneous, blood system, circulatory system, nervous system, digestive system, respiratory system, aiming to provide reference for clinical work.


Assuntos
Criança , Recém-Nascido , Feminino , Gravidez , Humanos , Lúpus Eritematoso Sistêmico/diagnóstico , Prognóstico , Autoanticorpos , Família
2.
Chinese Journal of Preventive Medicine ; (12): 935-940, 2023.
Artigo em Chinês | WPRIM | ID: wpr-985499

RESUMO

The incidence of perinatal disease and perinatal mortality in small for gestational age infants increased significantly. This group of people is prone to a variety of long-term metabolic diseases and cardiovascular diseases, and is also prone to growth retardation and neurodevelopmental delay, which will seriously affect the long-term quality of life of children. The article studies the neurodevelopmental outcomes of small-for-gestational-age infants. By reviewing and sorting out previous literature, the neurodevelopmental disorders of small-for-gestational-age infants are analyzed according to five aspects: intellectual development, motor development, language development, sensory development, and mental illness. The classification and summary were carried out, and the influencing factors of neurodevelopmental disorders of SGA were also evaluated, so as to provide reference for promoting the improvement of neurodevelopmental outcomes of small-for-gestational-age infants.


Assuntos
Recém-Nascido , Gravidez , Feminino , Criança , Lactente , Humanos , Idade Gestacional , Qualidade de Vida , Recém-Nascido Pequeno para a Idade Gestacional , Retardo do Crescimento Fetal/epidemiologia
3.
Chinese Journal of Contemporary Pediatrics ; (12): 415-419, 2023.
Artigo em Chinês | WPRIM | ID: wpr-981972

RESUMO

Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease that affects multiple organs and systems. It is more common in women of childbearing age. Compared with the general population, pregnant women with SLE are at a significantly increased risk of adverse perinatal outcomes such as preterm birth and intrauterine growth restriction. In addition, the offspring of SLE patients may also be adversely affected by in utero exposure to maternal autoantibodies, cytokines, and drugs. This article summarizes the long-term developmental outcomes of offspring of pregnant women with SLE in terms of the blood system, circulatory system, nervous system, and immune system.


Assuntos
Gravidez , Humanos , Feminino , Recém-Nascido , Resultado da Gravidez/epidemiologia , Gestantes , Complicações na Gravidez/epidemiologia , Nascimento Prematuro/etiologia , Lúpus Eritematoso Sistêmico
4.
Chinese Journal of Contemporary Pediatrics ; (12): 242-247, 2021.
Artigo em Chinês | WPRIM | ID: wpr-879840

RESUMO

OBJECTIVE@#To study the perinatal complications of late preterm twins (LPTs) versus early term twins (ETTs).@*METHODS@#A retrospective analysis was performed for the complications of 246 LPTs, 496 ETTs, and their mothers. The risk factors for late preterm birth were analyzed. According to gestational age, the twins were divided into five groups: 34-34@*RESULTS@#Maternal hypertension, maternal thrombocytopenia, placenta previa, and premature rupture of membranes were independent risk factors for late preterm birth in twins (@*CONCLUSIONS@#Compared with ETTs, LPTs have an increased incidence of perinatal complications. The incidence of perinatal complications is associated with gestational ages in the LPTs and ETTs.


Assuntos
Feminino , Humanos , Lactente , Recém-Nascido , Gravidez , Idade Gestacional , Nascimento Prematuro , Síndrome do Desconforto Respiratório do Recém-Nascido , Estudos Retrospectivos , Gêmeos
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