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Objective:To investigate the diagnostic value of frame stereotactic biopsy in patients with small solid tumors in the suprasellar region.Methods:From April 2018 to December 2020, 42 patients with solid tumors in the suprasellar region were selected in our hospital. All patients underwent frame stereotactic biopsy under multimodal image guidance. The imaging characteristics, histological and pathological diagnosis rate, and incidence of biopsy complications of these patients were analyzedResults:(1) CT examination showed that the suprasellar cistern lesions were lumpy and well defined; 41 had high/slightly high density and 1 had calcification. MRI examination showed that the lesions were also lumpy and the signal was relatively uniform; enhanced images showed that 3 patients had "salt and pepper sign"; Magnetic Resonance Spectrum showed that 2 had typical huge Lip composite peak. (2) All 42 patients underwent frame stereotactic biopsy successfully, and 35 patients (83.3%) were pathologically diagnosed, including 24 with germinoma (GE), one with embryonal carcinoma, 6 with Langerhans histiocytosis (LCH), 2 with hair-cell astrocytoma, and 2 with diffuse large B-cell lymphoma. Postoperative head CT showed that two were with micro-hemorrhage in the operation area, and the rest showed no signs of hemorrhage. No significant changes were observed in the clinical manifestations before and after surgery.Conclusion:Frame-based stereotactic biopsy is safe and reliable, with few surgical complications and high diagnosis rate in small solid tumors in the suprasellar region.
RESUMO
Objective:To investigate the clinical and neuroimaging features of atypical teratoid/rhabdoid tumors (AT/RT) of the central nervous system and the survival prognosis in different locations.Methods:The clinical data of 27 patients with AT/RT confirmed by biopsy or postoperative pathology in Sanbo Brain Hospital of Capital Medical University from October 2012 to September 2020 were collected, including 17 males and 10 females, aged (7.6±10.0) years, ranging from 0.2 to 39.0 years old.The clinical features and the results of the first preoperative imaging examination were retrospectively analyzed.The patients were divided into supratentorial, infratentorial and trans supratentorial and infratentorial groups according to the location.The survival time of the three groups was compared by Kaplan-Meier survival curve.Results:All patients presented with headache, including 12 cases with vomiting.There were 12 cases of supratentorial, 10 cases of infratentorial and 5 cases of supratentorial and infratentorial.There were 20 cases of cystic degeneration, 7 cases of calcification, 6 cases of hemorrhage and 13 cases of peritumoral edema.The median survival time of patients with infratentorial AT/RT was longer than that of patients with supratentorial and transtentorial AT/RT (χ 2=7.353, P=0.025). Conclusion:Central nervous system AT/RT is easy to occur in young children, and the survival time of AT/RT patients is longer.